Niinimäki A, Björkstén F, Puukka M, Tolonen K, Hannuksela M
Department of Dermatology, Oulu University Central Hospital, Finland.
Allergy. 1989 Jan;44(1):60-5. doi: 10.1111/j.1398-9995.1989.tb00447.x.
Skin prick tests (SPT) with freeze-dried spices and 5% (w/v) spice extracts were performed on 50 patients with 2+ or stronger SPT reactions to spices per se, and RAST were performed on 10 of them. Freeze-dried extracts produced mostly equal or stronger SPT reactions than corresponding whole spices, but 5% (w/v) extracts produced weaker reactions and also remained totally negative in some patients. Positive RAST results were seen in all 10 patients tested. The correlation between the RAST and SPT results was good for mustard and paprika, but poor for cayenne, coriander, caraway and white pepper. Five patients with positive SPT and RAST for spices contracted rhinitis from powdered spices in their working environments, and one patient suffered from gastrointestinal pains caused by spiced food. The others had noticed no clinical symptoms caused by spices. The present results thus indicate that both SPT and RAST should include purified spice extracts.
对50名对香料本身皮肤点刺试验（SPT）反应为2+或更强的患者进行了冻干香料和5%（w/v）香料提取物的皮肤点刺试验，并对其中10名患者进行了放射性变应原吸附试验（RAST）。冻干提取物产生的SPT反应大多与相应的完整香料相同或更强，但5%（w/v）提取物产生的反应较弱，并且在一些患者中完全呈阴性。所有10名接受测试的患者RAST结果均为阳性。RAST和SPT结果之间的相关性在芥末和辣椒粉方面良好，但在辣椒、香菜、葛缕子和白胡椒方面较差。5名香料SPT和RAST呈阳性的患者在工作环境中因接触粉末状香料而患上鼻炎，1名患者因食用加香料的食物而出现肠胃疼痛。其他人未注意到香料引起临床症状。因此，目前的结果表明，SPT和RAST均应包括纯化的香料提取物。
