Niinimäki A, Hannuksela M
Allergy. 1981 Oct;36(7):487-93. doi: 10.1111/j.1398-9995.1981.tb01860.x.
Scratch tests with common spices were performed in 1,120 atopic and 380 non-atopic patients. Positive skin test reactions were seen almost exclusively in atopics. Curry and paprika produced reactions most frequently, and when the components of curry were tested separately, coriander, caraway, cayenne and mustard were responsible for the vast majority of the skin reactions. A high correlation between positive skin test reactions to spices, especially to curry and its components, and tree pollens, fruits and vegetables was demonstrated, suggesting that there may be a group of cross allergies. Clinical symptoms from ingested spices were noticed by five patients. When small amounts of spices were spread on the oral mucosa, local reactions, especially in the mouth and nasopharynx, were found in 14 out of 35 unselected patients with positive skin test reactions. Peroral challenges with spices in gelatin capsules were negative in 20 nonselected patients.
对1120名特应性患者和380名非特应性患者进行了常见香料的划痕试验。几乎仅在特应性患者中观察到阳性皮肤试验反应。咖喱和辣椒粉引起的反应最为频繁，当分别测试咖喱的成分时，香菜、葛缕子、辣椒和芥末是绝大多数皮肤反应的原因。结果表明，对香料尤其是咖喱及其成分的阳性皮肤试验反应与树花粉、水果和蔬菜之间存在高度相关性，提示可能存在一组交叉过敏。5名患者注意到摄入香料后出现临床症状。在35名皮肤试验反应阳性的未选定患者中，有14名患者在口腔黏膜上涂抹少量香料后出现局部反应，尤其是口腔和鼻咽部。20名未选定患者口服明胶胶囊中的香料激发试验结果为阴性。
