Li Yayong, Wang Yina
Department of Emergency, The Third Xiangya Hospital of Central South University, Tong-ZiPo Road No.138, Changsha, Hunan, 410013, People's Republic of China.
Department of Geriatrics, The Second Xiangya Hospital of Central South University, Middle Ren-Min Road No.139, Changsha, Hunan, 410011, People's Republic of China.
Sleep Breath. 2016 Dec;20(4):1255-1261. doi: 10.1007/s11325-016-1354-8. Epub 2016 May 18.
Upper airway symptom associated with continuous positive airway pressure (CPAP) treatment is an important factor influencing CPAP adherence. There are conflicting data on the effect of a heated humidifier (HH) during CPAP titration for patients with obstructive sleep apnea hypopnea syndrome (OSAHS). This study investigated the effects of HH during CPAP titration in the cool sleeping environment.
Forty newly diagnosed OSAHS patients who received CPAP titration in the cool sleeping environment were randomly assigned to HH and non-HH groups. A questionnaire was used to evaluate upper airway symptoms, satisfaction with initial CPAP treatment, and willingness to further use CPAP. Some therapy parameters including leak, apnea hypopnea index (AHI) reduction, and optimal CPAP pressure level were analyzed. We compared these subjective and objective data between the two groups.
In subjective sensation, the use of HH can alleviate upper airway symptoms associated with CPAP titration (P < 0.001). The HH group has benefit in satisfaction with initial CPAP treatment (P < 0.001) and further willingness to use CPAP (P < 0.01), although there were no significant differences in leak, AHI reduction, and optimal CPAP pressure between the two groups.
The use of HH is recommended during CPAP titration in the cool sleeping environment because of its benefit in the treatment of upper airway symptoms associated with CPAP therapy and improvement of the CPAP acceptance.
与持续气道正压通气(CPAP)治疗相关的上气道症状是影响CPAP依从性的重要因素。对于阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者,在CPAP滴定期间使用加热湿化器(HH)的效果存在相互矛盾的数据。本研究调查了在凉爽睡眠环境中CPAP滴定期间HH的作用。
40例在凉爽睡眠环境中接受CPAP滴定的新诊断OSAHS患者被随机分为HH组和非HH组。使用问卷评估上气道症状、对初始CPAP治疗的满意度以及进一步使用CPAP的意愿。分析了一些治疗参数,包括漏气、呼吸暂停低通气指数(AHI)降低和最佳CPAP压力水平。我们比较了两组之间的这些主观和客观数据。
在主观感受方面,使用HH可减轻与CPAP滴定相关的上气道症状(P < 0.001)。HH组在对初始CPAP治疗的满意度(P < 0.001)和进一步使用CPAP的意愿方面有优势(P < 0.01),尽管两组在漏气、AHI降低和最佳CPAP压力方面无显著差异。
在凉爽睡眠环境中进行CPAP滴定期间建议使用HH,因为它有助于治疗与CPAP治疗相关的上气道症状并提高CPAP的接受度。