Yetkin Ozkan, Kunter Erdogan, Gunen Hakan
Department of Pulmonary Medicine, Faculty of Medicine, Inonu University, 44069 Malatya, Turkey.
Sleep Breath. 2008 Nov;12(4):365-7. doi: 10.1007/s11325-008-0188-4. Epub 2008 May 15.
Obstructive sleep apnea syndrome (OSAS) is characterized by repeated cessations of breathing during sleep. Major symptoms of this disease are excessive daytime sleepiness, snoring, and witnessed apnea. Most of the patients are treated with CPAP. In this study, we aimed to evaluate the factors affecting adherence to the CPAP treatment. Seventy-one patients were enrolled to this study. Patients were divided into three groups according to CPAP usage. Group I consisted of patients who had never used CPAP, group II consisted of patients who had used CPAP occasionally, and group-III patients had used CPAP treatment regularly. Group-III patients had higher apnea-hypopnea index (AHI) than groups I and II (respectively, 56.6 +/- 27.7, 26.3 +/- 7.5, and 32.3 +/- 7.06; p < 0.000 for both). Oxygen desaturation index was significantly higher in group-III patients comparing to groups I and II (44.6 +/- 22.3, 15.9 +/- 8.3, and 25.6 +/- 9.5; p < 0.000 for all). Our findings have shown that only very severe patients use the CPAP device regularly (mean AHI 56.6 +/- 27.7). Compliance to CPAP treatment seemed to be poor in patients with moderate to severe, AHI about 30, OSAS. Considering the well-established benefits of CPAP treatment in patients with true indications, patients should be encouraged to use CPAP regularly, and complications of OSAS should be keynoted.
阻塞性睡眠呼吸暂停综合征(OSAS)的特征是睡眠期间呼吸反复停止。这种疾病的主要症状是白天过度嗜睡、打鼾和观察到的呼吸暂停。大多数患者接受持续气道正压通气(CPAP)治疗。在本研究中,我们旨在评估影响CPAP治疗依从性的因素。71名患者纳入本研究。根据CPAP使用情况将患者分为三组。第一组由从未使用过CPAP的患者组成,第二组由偶尔使用CPAP的患者组成,第三组患者定期使用CPAP治疗。第三组患者的呼吸暂停低通气指数(AHI)高于第一组和第二组(分别为56.6±27.7、26.3±7.5和32.3±7.06;两组比较p均<0.000)。与第一组和第二组相比,第三组患者的氧饱和度下降指数显著更高(分别为44.6±22.3、15.9±8.3和25.6±9.5;所有比较p均<0.000)。我们的研究结果表明,只有非常严重的患者才会定期使用CPAP设备(平均AHI为56.6±27.7)。对于中重度AHI约为30的OSAS患者,CPAP治疗的依从性似乎较差。考虑到CPAP治疗对真正有适应症患者已明确的益处,应鼓励患者定期使用CPAP,并强调OSAS的并发症。