人血浆蛋白的高分辨率二维电泳
High resolution two-dimensional electrophoresis of human plasma proteins.
作者信息
Anderson L, Anderson N G
出版信息
Proc Natl Acad Sci U S A. 1977 Dec;74(12):5421-5. doi: 10.1073/pnas.74.12.5421.
Abstract
The two-dimensional electrophoretic technique of O'Farrell has been adapted to the analysis of human plasma proteins, and 30 polypeptides have been identified in the pattern produced. Genetic variants involving charge (isoelectric point) or size (molecular weight in the presence of sodium dodecyl sulfate) changes should be routinely detectable in at least 20 proteins at once, facilitating studies of human mutation rates.
摘要
奥法雷尔的二维电泳技术已被应用于人类血浆蛋白的分析，并且在所产生的图谱中已鉴定出30种多肽。涉及电荷（等电点）或大小（在十二烷基硫酸钠存在下的分子量）变化的遗传变异应该能够同时在至少20种蛋白质中常规检测到，这便于对人类突变率进行研究。
Zotero 插件