Nassiri-Asl Marjan, Hosseinzadeh Hossein
Cellular and Molecular Research Center, Department of Pharmacology, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Pharmaceutical Research Center, Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Phytother Res. 2016 Sep;30(9):1392-403. doi: 10.1002/ptr.5644. Epub 2016 May 16.
Vitis vinifera fruit (grape) contains various phenolic compounds, flavonoids and stilbenes. In recent years, active constituents found in the fruits, seeds, stems, skin and pomaces of grapes have been identified and some have been studied. In this review, we summarize the active constituents of different parts of V. vinifera and their pharmacological effects including skin protection, antioxidant, antibacterial, anticancer, antiinflammatory and antidiabetic activities, as well as hepatoprotective, cardioprotective and neuroprotective effects in experimental studies published after our 2009 review. Clinical and toxicity studies have also been examined. Copyright © 2016 John Wiley & Sons, Ltd.
酿酒葡萄果实（葡萄）含有多种酚类化合物、黄酮类化合物和芪类化合物。近年来，已鉴定出葡萄果实、种子、茎、皮和果渣中的活性成分，其中一些已得到研究。在本综述中，我们总结了酿酒葡萄不同部位的活性成分及其药理作用，包括皮肤保护、抗氧化、抗菌、抗癌、抗炎和抗糖尿病活性，以及在我们2009年综述之后发表的实验研究中的肝脏保护、心脏保护和神经保护作用。还审查了临床和毒性研究。版权所有© 2016约翰威立父子有限公司。
