Suppr超能文献

探索从孟加拉国本土可食用水果中提取的植物化学物质的神经保护益处。

Exploring the neuroprotective benefits of phytochemicals extracted from indigenous edible fruits in Bangladesh.

作者信息

Roy Sumon, Roy Sajib Chandra, Zehravi Mehrukh, Sweilam Sherouk Hussein, Das Rajib, Palanisamy Mylsamy, Dantinapalli Venkata Lakshamana Sagar, Elumalai Selvaraja, Gupta Jeetendra Kumar, Alshehri Mohammed Ali, Asiri Mohammed, Ahmad Irfan, Nafady Mohamed H, Emran Talha Bin

机构信息

Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh.

Department of Clinical Pharmacy, College of Dentistry & Pharmacy, Buraydah Private Colleges, Buraydah, Saudi Arabia.

出版信息

Animal Model Exp Med. 2025 Feb;8(2):239-265. doi: 10.1002/ame2.12522. Epub 2025 Jan 14.

Abstract

The increasing incidence of neurodegenerative diseases (NDs) and the constraints of existing treatment methods have spurred a keen interest in investigating alternative therapies. Medicinal plants, renowned for their long-standing use in traditional medicine, offer a hopeful avenue for discovering new neuroprotective agents. This study emphasizes the potential neuroprotective characteristics of edible fruit plants in Bangladesh, specifically focusing on their traditional folk medicine uses for neurological disorders. This study provides an in-depth overview of the different types of edible fruit trees in Bangladesh and their phytochemicals, including flavonoids, terpenoids, and phenolic acids. This work examines the scientific data supporting the neuroprotective properties of bioactive chemicals from plants. It further explores the mechanisms by which these compounds work to counteract oxidative stress, decrease inflammation, and stimulate neurogenesis. Moreover, the study investigates toxicological characteristics and bioactive components of some fruits, emphasizing the importance of further investigation to measure their safety profile comprehensively. This thorough study highlights the potential benefits of Bangladesh's edible fruit trees as a rich source of neuroprotective chemicals. It also shows that additional research might lead to novel approaches for improving brain functioning and preventing NDs.

摘要

神经退行性疾病(NDs)发病率的不断上升以及现有治疗方法的局限性,激发了人们对研究替代疗法的浓厚兴趣。药用植物长期以来在传统医学中使用,为发现新的神经保护剂提供了一条充满希望的途径。本研究强调了孟加拉国可食用水果植物潜在的神经保护特性,特别关注它们在传统民间医学中用于治疗神经系统疾病的用途。本研究深入概述了孟加拉国不同类型的可食用果树及其植物化学物质,包括黄酮类化合物、萜类化合物和酚酸。这项工作审视了支持植物生物活性化学物质神经保护特性的科学数据。它进一步探索了这些化合物对抗氧化应激、减轻炎症和刺激神经发生的作用机制。此外,该研究调查了一些水果的毒理学特性和生物活性成分,强调了进一步研究以全面衡量其安全性的重要性。这项深入的研究突出了孟加拉国可食用果树作为丰富神经保护化学物质来源的潜在益处。它还表明,进一步的研究可能会带来改善大脑功能和预防神经退行性疾病的新方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a24/11871099/c16852d7c108/AME2-8-239-g003.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验