• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

丘脑底核刺激治疗帕金森病缓解蜘蛛恐惧症

Arachnophobia alleviated by subthalamic nucleus stimulation for Parkinson's disease.

作者信息

Allert Niels, Gippert Sabrina M, Sajonz Bastian E A, Nelles Christoph, Bewernick Bettina, Schlaepfer Thomas E, Coenen Volker A

机构信息

Neurological Rehabilitation Center Godeshoehe, Waldstrasse 2-10, 53177, Bonn, Germany.

Department of Psychiatry and Psychotherapy, Bonn University Medical Center, Sigmund-Freud-Strasse 25, 53105, Bonn, Germany.

出版信息

J Neural Transm (Vienna). 2016 Jun;123(6):631-5. doi: 10.1007/s00702-016-1546-1. Epub 2016 May 19.

DOI:10.1007/s00702-016-1546-1
PMID:27198699
Abstract

We report on a Parkinson patient with motor fluctuations and dyskinesias in whom deep brain stimulation (DBS) of the subthalamic nucleus (STN) not only improved motor symptoms but also pre-existing arachnophobia. Arachnophobia had been unchanged by the course of Parkinson's disease but rapidly improved with STN-DBS. Both, motor effects and the improvement of arachnophobia were stable during 2 years follow-up. To our knowledge this is the first report on STN stimulation effects on a specific phobia.

摘要

我们报告了一名患有运动波动和异动症的帕金森病患者,其丘脑底核(STN)的深部脑刺激(DBS)不仅改善了运动症状,还改善了原有的恐蛛症。帕金森病病程中恐蛛症一直未变,但STN-DBS使其迅速改善。在2年的随访期间,运动效果和恐蛛症的改善情况均保持稳定。据我们所知,这是关于STN刺激对特定恐惧症影响的首例报告。

相似文献

1
Arachnophobia alleviated by subthalamic nucleus stimulation for Parkinson's disease.丘脑底核刺激治疗帕金森病缓解蜘蛛恐惧症
J Neural Transm (Vienna). 2016 Jun;123(6):631-5. doi: 10.1007/s00702-016-1546-1. Epub 2016 May 19.
2
Meta-analysis comparing deep brain stimulation of the globus pallidus and subthalamic nucleus to treat advanced Parkinson disease.比较苍白球和丘脑底核深部脑刺激治疗晚期帕金森病的荟萃分析。
J Neurosurg. 2014 Sep;121(3):709-18. doi: 10.3171/2014.4.JNS131711. Epub 2014 Jun 6.
3
Improving outcomes of subthalamic nucleus deep brain stimulation in Parkinson's disease.改善帕金森病丘脑底核深部脑刺激的疗效。
Expert Rev Neurother. 2015 Oct;15(10):1151-60. doi: 10.1586/14737175.2015.1081815. Epub 2015 Sep 17.
4
Subthalamic Nucleus Deep Brain Stimulation Modulate Catecholamine Levels with Significant Relations to Clinical Outcome after Surgery in Patients with Parkinson's Disease.丘脑底核深部脑刺激调节帕金森病患者术后儿茶酚胺水平,且与临床结局显著相关。
PLoS One. 2015 Sep 22;10(9):e0138462. doi: 10.1371/journal.pone.0138462. eCollection 2015.
5
Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial.苍白球内侧与丘脑底核双侧脑深部电刺激治疗晚期帕金森病的随机对照试验(NSTAPS 研究)
Lancet Neurol. 2013 Jan;12(1):37-44. doi: 10.1016/S1474-4422(12)70264-8. Epub 2012 Nov 16.
6
Comparative effects of unilateral and bilateral subthalamic nucleus deep brain stimulation on gait kinematics in Parkinson's disease: a randomized, blinded study.帕金森病中单侧与双侧丘脑底核深部脑刺激对步态运动学的比较影响:一项随机、盲法研究。
J Neurol. 2016 Aug;263(8):1652-6. doi: 10.1007/s00415-016-8191-3. Epub 2016 Jun 8.
7
Deep brain stimulation of the subthalamic nucleus for control of extrapyramidal features in advanced idiopathic parkinson's disease: one year follow-up.丘脑底核深部脑刺激术治疗晚期特发性帕金森病锥体外系症状的一年随访
J Neural Transm (Vienna). 1999;106(7-8):693-709. doi: 10.1007/s007020050190.
8
Long-term outcome of subthalamic nucleus DBS in Parkinson's disease: from the advanced phase towards the late stage of the disease?(subthalamic nucleus DBS)丘脑底核脑深部电刺激术在帕金森病中的长期疗效:从疾病的晚期到晚期?
Parkinsonism Relat Disord. 2014 Apr;20(4):376-81. doi: 10.1016/j.parkreldis.2014.01.012. Epub 2014 Jan 23.
9
Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up.帕金森病双侧脑深部电刺激:一项为期4年随访的多中心研究
Brain. 2005 Oct;128(Pt 10):2240-9. doi: 10.1093/brain/awh571. Epub 2005 Jun 23.
10
Medial forebrain bundle stimulation as a pathophysiological mechanism for hypomania in subthalamic nucleus deep brain stimulation for Parkinson's disease.内侧前脑束刺激作为帕金森病丘脑底核深部脑刺激中轻躁狂发作的一种病理生理机制。
Neurosurgery. 2009 Jun;64(6):1106-14; discussion 1114-5. doi: 10.1227/01.NEU.0000345631.54446.06.

本文引用的文献

1
The Subthalamic Nucleus, Limbic Function, and Impulse Control.丘脑底核、边缘系统功能与冲动控制
Neuropsychol Rev. 2015 Dec;25(4):398-410. doi: 10.1007/s11065-015-9306-9. Epub 2015 Nov 14.
2
Topographic organization of the human and non-human primate subthalamic nucleus.人类和非人类灵长类动物丘脑底核的拓扑组织。
Brain Struct Funct. 2015 Nov;220(6):3075-86. doi: 10.1007/s00429-015-1047-2. Epub 2015 Apr 29.
3
Functional anatomy of subthalamic nucleus stimulation in Parkinson disease.帕金森病中丘脑底核刺激的功能解剖学
Ann Neurol. 2014 Aug;76(2):279-95. doi: 10.1002/ana.24204. Epub 2014 Jul 2.
4
Mood and behavioural effects of subthalamic stimulation in Parkinson's disease.帕金森病患者丘脑底核刺激的情绪和行为影响。
Lancet Neurol. 2014 Mar;13(3):287-305. doi: 10.1016/S1474-4422(13)70294-1. Epub 2014 Feb 17.
5
Abolition of lifelong specific phobia: a novel therapeutic consequence of left mesial temporal lobectomy.终生特定恐惧症的消除:左侧颞叶内侧切除术的一种新型治疗效果。
Neurocase. 2015 Feb;21(1):79-84. doi: 10.1080/13554794.2013.873056. Epub 2014 Jan 27.
6
Meta-analysis of functional brain imaging in specific phobia.特定恐惧症的功能脑影像学荟萃分析。
Psychiatry Clin Neurosci. 2013 Jul;67(5):311-22. doi: 10.1111/pcn.12055. Epub 2013 May 28.
7
Functional neuroimaging in specific phobia.特定恐惧症的功能神经影像学。
Psychiatry Res. 2012 Jun 30;202(3):181-97. doi: 10.1016/j.pscychresns.2011.10.009. Epub 2012 Jul 16.
8
Human medial forebrain bundle (MFB) and anterior thalamic radiation (ATR): imaging of two major subcortical pathways and the dynamic balance of opposite affects in understanding depression.人类内侧额束(MFB)和前丘脑辐射(ATR):两种主要皮质下通路的成像与对抑郁症认识中相反影响的动态平衡
J Neuropsychiatry Clin Neurosci. 2012 Spring;24(2):223-36. doi: 10.1176/appi.neuropsych.11080180.
9
Mood response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease.帕金森病患者丘脑底核深部脑刺激的情绪反应。
J Neuropsychiatry Clin Neurosci. 2012 Winter;24(1):28-36. doi: 10.1176/appi.neuropsych.11030060.
10
Neuroimaging in specific phobia disorder: a systematic review of the literature.特定恐惧症障碍的神经影像学:文献系统综述。
Braz J Psychiatry. 2012 Mar;34(1):101-11.