Bassal Ravit, Lerner Larisa, Valinsky Lea, Agmon Vered, Peled Nehama, Block Colin, Keller Nati, Keness Yoram, Taran Diana, Shainberg Bracha, Ken-Dror Shifra, Treygerman Orit, Rouach Tsvi, Lowenthal Shulamit, Shohat Tamar, Cohen Daniel
1 Israel Center for Disease Control , Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel .
2 Sackler Faculty of Medicine, School of Public Health, Tel Aviv University , Tel Aviv, Israel .
Foodborne Pathog Dis. 2016 Aug;13(8):448-55. doi: 10.1089/fpd.2015.2096. Epub 2016 May 20.
The objective of this study was to examine the recent trends in the epidemiology of campylobacteriosis in Israel. A Sentinel Laboratory-Based Surveillance Network for Bacterial Enteric Diseases was established in Israel by the Israel Center for Disease Control (ICDC). This network generated data on subjects from whom Campylobacter spp. was isolated in community and hospital laboratories. Further characterization of the isolates was done at the Campylobacter National Reference Laboratory. Data from these two sources were integrated and analyzed at the ICDC. Between 1999 and 2012, 40,978 Campylobacter stool isolates were reported to the ICDC by the sentinel laboratories. The incidence rate of campylobacteriosis increased from 65.7 per 100,000 in 1999 to 101.7 per 100,000 in 2012. This increase resulted from a significant rise in the incidence of campylobacteriosis in the Jewish population which, since 2009, surpassed the consistent higher incidence of the disease in Israeli Arabs. The peak morbidity in Israel consistently occurred in late spring, with a risk excess in males compared with females, in younger age groups and earlier in the life span among Arabs than among Jews and others. These results suggest that further analytical studies should be carried out to identify risk factors responsible for the increased incidence of campylobacteriosis and better direct prevention and control of the disease in Israel.
本研究的目的是调查以色列弯曲菌病流行病学的近期趋势。以色列疾病控制中心（ICDC）在以色列建立了一个基于哨点实验室的细菌性肠道疾病监测网络。该网络收集了社区和医院实验室分离出弯曲杆菌属的受试者的数据。分离菌株的进一步鉴定在弯曲杆菌国家参考实验室进行。这两个来源的数据在ICDC进行整合和分析。1999年至2012年期间，哨点实验室向ICDC报告了40978份弯曲杆菌粪便分离株。弯曲菌病的发病率从1999年的每10万人65.7例增加到2012年的每10万人101.7例。这种增加是由于犹太人群中弯曲菌病发病率显著上升所致，自2009年以来，该发病率超过了以色列阿拉伯人一直较高的发病率。以色列的发病高峰一直出现在春末，男性发病率高于女性，在较年轻年龄组以及阿拉伯人的发病时间早于犹太人和其他人。这些结果表明，应开展进一步的分析研究，以确定导致以色列弯曲菌病发病率增加的危险因素，并更好地指导该病的预防和控制。
