Thomas W J, Bevan H E, Hooper D G, Downey E J
Department of Pediatrics, Naval Hospital, San Diego, California 92134-5000.
Cancer. 1989 Jun 1;63(11):2216-9. doi: 10.1002/1097-0142(19890601)63:11<2216::aid-cncr2820631126>3.0.co;2-8.
A 1-year-old infant with von Recklinghausen's neurofibromatosis was seen because of increasing clitoral enlargement over a 7-month period. The mother, who also had neurofibromatosis, was treated 2 years beforehand for an acoustic neuroma. The child was treated by radical clitorectomy. Pathologic examination revealed malignant schwannoma, a tumor not previously described in this site. Vincristine, dactinomycin, and cyclophosphamide chemotherapy was given for 2 years to prevent local recurrence and metastatic spread. The child remains tumor free 2.5 years after diagnosis.
