Ziai Wendy, Nyquist Paul, Hanley Daniel F
Department of Anesthesiology and Critical Care Medicine, Neurology and Neurosurgery, Johns Hopkins University, Baltimore, Maryland.
Department of Anesthesiology and Critical Care Medicine, Neurology, Neurosurgery, and General Internal Medicine, Johns Hopkins University, Baltimore, Maryland.
Semin Neurol. 2016 Jun;36(3):261-8. doi: 10.1055/s-0036-1582131. Epub 2016 May 23.
In recent decades, the surgical treatment of intracerebral hemorrhage (ICH) has become a focus of scientific inquest. This effort has been led by an international group of neurologists and neurosurgeons with the goal of studying functional recovery and developing new surgical techniques to facilitate improved clinical outcomes. Currently, the two most pressing ICH investigational goals are (1) early blood pressure control, and (2) safe hematoma volume reduction. Achieving these goals would support decision-making, level-of-care choices, and the global research strategy of developing biologically informed treatments. Herein the authors review conventional and minimally invasive surgical approaches to spontaneous ICH, articulating the scope of the problem, recent clinical trials, management issues, and relevant questions for future research. The authors propose that strategies using minimally invasive techniques including clot aspiration with stereotactic guidance may give better results with improved clinical outcomes compared with standard open surgical approaches.
近几十年来,脑出血(ICH)的外科治疗已成为科学探究的焦点。这项工作由一群国际神经学家和神经外科医生牵头,目的是研究功能恢复情况并开发新的外科技术以促进临床疗效的改善。目前,脑出血研究中最紧迫的两个目标是:(1)早期血压控制;(2)安全减少血肿量。实现这些目标将有助于决策制定、护理级别选择以及制定基于生物学知识的治疗方法的全球研究策略。本文作者回顾了自发性脑出血的传统和微创手术方法,阐述了问题的范围、近期临床试验、管理问题以及未来研究的相关问题。作者提出,与标准的开放手术方法相比,采用包括立体定向引导下血块抽吸术在内的微创技术的策略可能会取得更好的效果,改善临床疗效。