Horsnell Jonathan D, Kendall Catherine, Stone Nicholas
Department of Breast Surgery, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.
Department of Biophotonics Research, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK.
Lasers Med Sci. 2016 Aug;31(6):1143-9. doi: 10.1007/s10103-016-1959-y. Epub 2016 May 25.
The ability to use Raman spectroscopy to assess tissue in the operative theatre setting could be advantageous for both patients and clinicians. In this study, a method of overcoming the deleterious effects of theatre lighting on the Raman spectra is demonstrated. The effectiveness of this technique is highlighted both within the theatre setting and using human lymph node tissue. The portable MiniRam II Raman spectroscopy device that incorporated a 785-nm laser was used in all experiments. This is an important step towards the use of Raman spectroscopy as a means of analysing sentinel lymph nodes in patients who have been newly diagnosed with breast cancer.
在手术室环境中使用拉曼光谱评估组织的能力对患者和临床医生都可能具有优势。在本研究中，展示了一种克服手术室照明对拉曼光谱有害影响的方法。该技术在手术室环境以及使用人淋巴结组织方面的有效性均得到了凸显。所有实验均使用了配备785纳米激光的便携式MiniRam II拉曼光谱仪。这是朝着将拉曼光谱用作分析新诊断乳腺癌患者前哨淋巴结的手段迈出的重要一步。
