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肺移植受者中阿皮尤斯瓶霉和多育瓶霉混合播散性感染：重症监护病房中经全身和局部联合抗真菌治疗长期存活的罕见病例。

Scedosporium apiospermum and S. prolificans mixed disseminated infection in a lung transplant recipient: An unusual case of long-term survival with combined systemic and local antifungal therapy in intensive care unit.

作者信息

Balandin Bárbara, Aguilar Miriam, Sánchez Isabel, Monzón Araceli, Rivera Isabel, Salas Clara, Valdivia Miguel, Alcántara Sara, Pérez Aris, Ussetti Piedad

机构信息

Intensive Care Unit, Hospital Universitario Puerta de Hierro Majadahonda, Spain.

Department of Pneumology and Lung Transplant Unit, Hospital Universitario Puerta de Hierro Majadahonda, Spain.

出版信息

Med Mycol Case Rep. 2016 Apr 30;11:53-6. doi: 10.1016/j.mmcr.2016.04.006. eCollection 2016 Mar.

DOI:10.1016/j.mmcr.2016.04.006
PMID:27222774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4865649/
Abstract

Infections due Scedosporium spp. in lung transplant recipients are associated with disseminated disease with high mortality rates. The adjunctive local antifungal therapy may be a useful option when systemic treatment is insufficient and/or surgery is not feasible. We present a case of mixed disseminated infection due Scedosporium apiospermum and S. prolificans in a lung transplant recipient. Combined local and systemic antifungal therapy provided an unusual long-term survival in the intensive care unit.

摘要

肺移植受者感染拟青霉属真菌与播散性疾病相关，死亡率很高。当全身治疗不足和/或手术不可行时，辅助局部抗真菌治疗可能是一种有用的选择。我们报告一例肺移植受者发生皮氏拟青霉和多育拟青霉混合播散性感染的病例。局部和全身联合抗真菌治疗使患者在重症监护病房获得了罕见的长期生存。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/fac8bde2a71a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/5c8cc96c0b26/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/6020e6d02425/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/7d8236c4ad34/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/fac8bde2a71a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/5c8cc96c0b26/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/6020e6d02425/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/7d8236c4ad34/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a450/4865649/fac8bde2a71a/gr4.jpg

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