人体肥胖与代谢综合征的外周血流调节。
Peripheral Blood Flow Regulation in Human Obesity and Metabolic Syndrome.
机构信息
1Department of Anesthesiology, Mayo Clinic, Rochester, MN; and Departments of 2Kinesiology and 3Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI.
出版信息
Exerc Sport Sci Rev. 2016 Jul;44(3):116-22. doi: 10.1249/JES.0000000000000083.
Abstract
Both obesity and metabolic syndrome are important cardiovascular disease risk factors. In this review, we will explore the hypothesis that young obese adults and adults with metabolic syndrome exhibit alterations in blood flow regulation that occur prior to the onset of overt cardiovascular dysfunction.
摘要
肥胖和代谢综合征都是重要的心血管疾病危险因素。在这篇综述中，我们将探讨这样一个假设，即年轻肥胖成年人和代谢综合征患者表现出血流调节的改变，这些改变发生在明显的心血管功能障碍之前。
相似文献
1
Peripheral Blood Flow Regulation in Human Obesity and Metabolic Syndrome.人体肥胖与代谢综合征的外周血流调节。
Exerc Sport Sci Rev. 2016 Jul;44(3):116-22. doi: 10.1249/JES.0000000000000083.
2
The effect of increasing body mass index on cardio-metabolic risk and biomarkers of oxidative stress and inflammation in nascent metabolic syndrome.体重指数增加对初发代谢综合征患者心血管代谢风险及氧化应激和炎症生物标志物的影响。
J Diabetes Complications. 2017 May;31(5):810-813. doi: 10.1016/j.jdiacomp.2017.02.010. Epub 2017 Feb 27.
3
Exercise training dose differentially alters muscle and heart capillary density and metabolic functions in an obese rat with metabolic syndrome.运动训练剂量对患有代谢综合征的肥胖大鼠的肌肉和心脏毛细血管密度及代谢功能有不同影响。
Exp Physiol. 2017 Dec 1;102(12):1716-1728. doi: 10.1113/EP086416. Epub 2017 Oct 26.
4
Noninvasive assessment of sympathetic vasoconstriction in human and rodent skeletal muscle using near-infrared spectroscopy and Doppler ultrasound.使用近红外光谱和多普勒超声对人和啮齿动物骨骼肌交感神经血管收缩进行无创评估。
J Appl Physiol (1985). 2004 Apr;96(4):1323-30. doi: 10.1152/japplphysiol.01041.2003. Epub 2003 Dec 2.
5
Vascular function in the metabolic syndrome and the effects on skeletal muscle perfusion: lessons from the obese Zucker rat.代谢综合征中的血管功能及其对骨骼肌灌注的影响：来自肥胖 Zucker 大鼠的启示
Essays Biochem. 2006;42:145-61. doi: 10.1042/bse0420145.
6
Paring down obesity and metabolic disease by targeting inflammation and oxidative stress.通过针对炎症和氧化应激来减轻肥胖和代谢性疾病。
Curr Neurovasc Res. 2015;12(2):107-8. doi: 10.2174/1567202612666150311101551.
7
Regulation of adipose tissue energy availability through blood flow control in the metabolic syndrome.通过代谢综合征中的血流控制调节脂肪组织能量供应。
Free Radic Biol Med. 2012 May 15;52(10):2108-19. doi: 10.1016/j.freeradbiomed.2012.03.003. Epub 2012 Apr 18.
8
A paradigm shift for local blood flow regulation.局部血流调节的范式转变。
J Appl Physiol (1985). 2014 Mar 15;116(6):703-5. doi: 10.1152/japplphysiol.00964.2013. Epub 2013 Oct 31.
9
Excessive consumption of fructose causes cardiometabolic dysfunctions through oxidative stress and inflammation.过量摄入果糖会通过氧化应激和炎症导致心脏代谢功能障碍。
Can J Physiol Pharmacol. 2017 Oct;95(10):1078-1090. doi: 10.1139/cjpp-2016-0663. Epub 2017 Feb 10.
10
Exercise-induced inhibition of angiotensin II vasoconstriction in human thigh muscle.运动诱导的人体大腿肌肉中血管紧张素II血管收缩的抑制作用。
J Physiol. 2006 Dec 1;577(Pt 2):727-37. doi: 10.1113/jphysiol.2006.113977. Epub 2006 Sep 14.
引用本文的文献
1
A lightGBM-based method for the signal quality assessment of wrist photoplethysmography.一种基于LightGBM的手腕光电容积脉搏波信号质量评估方法。
Phys Eng Sci Med. 2025 Aug 19. doi: 10.1007/s13246-025-01616-z.
2
The predictors of coronary slow flow in patients undergoing coronary angiography.接受冠状动脉造影患者冠状动脉血流缓慢的预测因素。
Egypt Heart J. 2024 Aug 13;76(1):103. doi: 10.1186/s43044-024-00536-9.
3
Impaired Vastus Lateralis Blood Flow During Cycling Exercise in Heart Failure With Preserved Ejection Fraction.射血分数保留的心力衰竭患者在骑自行车运动期间股外侧肌血流受损。
J Card Fail. 2024 Dec;30(12):1637-1640. doi: 10.1016/j.cardfail.2024.04.025. Epub 2024 May 20.
4
A novel function of CREG in metabolic disorders.CREG在代谢紊乱中的一种新功能。
Med Rev (2021). 2022 Jan 11;1(1):18-22. doi: 10.1515/mr-2021-0031. eCollection 2021 Oct.
5
Advances in Photoplethysmography for Personalized Cardiovascular Monitoring.光电容积脉搏波技术在个性化心血管监测中的进展。
Biosensors (Basel). 2022 Oct 12;12(10):863. doi: 10.3390/bios12100863.
6
Skeletal Muscle Microvascular Dysfunction in Obesity-Related Insulin Resistance: Pathophysiological Mechanisms and Therapeutic Perspectives.肥胖相关胰岛素抵抗中的骨骼肌微血管功能障碍：病理生理机制和治疗展望。
Int J Mol Sci. 2022 Jan 13;23(2):847. doi: 10.3390/ijms23020847.
7
Preserved β-adrenergic-mediated vasodilation in skeletal muscle of young adults with obesity despite shifts in cyclooxygenase and nitric oxide synthase.肥胖青年的骨骼肌中β肾上腺素能介导的血管舒张功能得以保留，尽管环氧化酶和一氧化氮合酶发生了转移。
Am J Physiol Heart Circ Physiol. 2022 Jan 1;322(1):H25-H35. doi: 10.1152/ajpheart.00449.2021. Epub 2021 Nov 5.
8
Sources of Inaccuracy in Photoplethysmography for Continuous Cardiovascular Monitoring.光电容积脉搏波法用于连续心血管监测的不准确性来源。
Biosensors (Basel). 2021 Apr 16;11(4):126. doi: 10.3390/bios11040126.
9
Evaluation of the Effects of Acarbose on Weight and Metabolic, Inflammatory, and Cardiovascular Markers in Patients with Obesity and Overweight.阿卡波糖对肥胖和超重患者体重及代谢、炎症和心血管指标影响的评估
Int J Prev Med. 2020 Sep 5;11:140. doi: 10.4103/ijpvm.IJPVM_229_19. eCollection 2020.
10
Effect of Combined Mental Task and Metaboreflex Activation on Hemodynamics and Cerebral Oxygenation in Patients With Metabolic Syndrome.联合心理任务与代谢反射激活对代谢综合征患者血流动力学和脑氧合的影响
Front Physiol. 2020 May 14;11:397. doi: 10.3389/fphys.2020.00397. eCollection 2020.
本文引用的文献
1
Preserved Microvascular Endothelial Function in Young, Obese Adults with Functional Loss of Nitric Oxide Signaling.一氧化氮信号功能丧失的年轻肥胖成年人微血管内皮功能得以保留。
Front Physiol. 2015 Dec 22;6:387. doi: 10.3389/fphys.2015.00387. eCollection 2015.
2
Increased peripheral vascular disease risk progressively constrains perfusion adaptability in the skeletal muscle microcirculation.外周血管疾病风险增加会逐渐限制骨骼肌微循环中的灌注适应性。
Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H488-504. doi: 10.1152/ajpheart.00790.2015. Epub 2015 Dec 23.
3
Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs.运动期间对肌肉血流量增加（充血）的调节：相互竞争的生理需求层次。
Physiol Rev. 2015 Apr;95(2):549-601. doi: 10.1152/physrev.00035.2013.
4
Neural control of the circulation: how sex and age differences interact in humans.循环系统的神经控制：人类性别与年龄差异如何相互作用。
Compr Physiol. 2015 Jan;5(1):193-215. doi: 10.1002/cphy.c140005.
5
Obesity-induced increases in sympathetic nerve activity: sex matters.肥胖引起的交感神经活动增加：性别因素很重要。
Auton Neurosci. 2015 Jan;187:18-26. doi: 10.1016/j.autneu.2014.11.006. Epub 2014 Nov 20.
6
Exercise-mediated vasodilation in human obesity and metabolic syndrome: effect of acute ascorbic acid infusion.运动介导的人类肥胖和代谢综合征中的血管扩张：急性抗坏血酸输注的影响。
Am J Physiol Heart Circ Physiol. 2014 Sep 15;307(6):H840-7. doi: 10.1152/ajpheart.00312.2014. Epub 2014 Jul 18.
7
Mechanical and metabolic reflex activation of the sympathetic nervous system in younger adults with metabolic syndrome.代谢综合征年轻患者交感神经系统的机械和代谢反射激活。
Auton Neurosci. 2014 Jul;183:100-5. doi: 10.1016/j.autneu.2014.03.003. Epub 2014 Mar 13.
8
Neural control of blood flow during exercise in human metabolic syndrome.人类代谢综合征运动期间血流的神经控制
Exp Physiol. 2014 Sep;99(9):1191-202. doi: 10.1113/expphysiol.2014.078048. Epub 2014 Mar 21.
9
Microvascular function in younger adults with obesity and metabolic syndrome: role of oxidative stress.肥胖和代谢综合征的年轻成年人的微血管功能：氧化应激的作用。
Am J Physiol Heart Circ Physiol. 2013 Oct 15;305(8):H1230-7. doi: 10.1152/ajpheart.00291.2013. Epub 2013 Aug 9.
10
Peripheral circulation.外周循环。
Compr Physiol. 2012 Jan;2(1):321-447. doi: 10.1002/cphy.c100048.
Zotero 插件