Timucin Ozgur Bulent, Karadag Mehmet Fatih, Aslanci Mehmet Emin, Baykara Mehmet
Department of Ophthalmology, Istanbul Hospital, Van, Turkey.
Department of Ophthalmology, School of Medicine, Uludag University, Bursa, Turkey.
Arq Bras Oftalmol. 2016 Apr;79(2):121-2. doi: 10.5935/0004-2749.20160036.
We report the case of a 70-year-old female patient who developed corneal edema and iris discoloration following the inadvertent use of 1% methylene blue instead of 0.025% trypan blue to stain the anterior capsule during cataract phacoemulsification surgery. Copious irrigation was performed upon realization of incorrect dye use. Corneal edema and iris discoloration developed during the early postoperative period and persisted at 24-months follow-up. However, keratoplasty was not required. The intracameral use of 1% methylene blue has a cytotoxic effect on the corneal endothelium and iris epithelium. Copious irrigation for at least 30 min using an anterior chamber maintainer may improve outcomes.
我们报告了一例70岁女性患者的病例，该患者在白内障超声乳化手术中不慎使用1%亚甲蓝而非0.025%台盼蓝对前囊进行染色后，出现了角膜水肿和虹膜变色。在意识到染料使用错误后进行了大量冲洗。角膜水肿和虹膜变色在术后早期出现，并在24个月的随访中持续存在。然而，不需要进行角膜移植。前房内使用1%亚甲蓝对角膜内皮和虹膜上皮具有细胞毒性作用。使用前房维持器进行至少30分钟的大量冲洗可能会改善预后。
