School of Mechanical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Sci Rep. 2016 May 27;6:27006. doi: 10.1038/srep27006.
Antimicrobial nanobunches with different amounts of chitosan-capped Ag were prepared by continuous gas-liquid green route under ultrasound irradiation. Spark-produced aerosol Cu nanoparticles were directly injected into an ultrasound Ag(I)-chitosan reaction cell for efficient hydrosolization of the Cu particles and the subsequent incorporation of Ag and chitosan on Cu. Subsequently, electrospraying was used to form of chitosan-capped Cu-Ag nanobunch coatings. The time required for reducing the bacterial proliferation to 50% dropped to ~1 h at a nanobunch concentration of 10 μg mL(-1) from the 2.0 min Ag(I) reaction time, and was further decreased to ~0.5 h by increasing the concentration of the nanobunches to 90 μg mL(-1). The nanobunches were directly coated onto the substrate using an electrospray device to fabricate transparent films and composite fibers. The antimicrobial activity of the composite carbon fibers was then evaluated via the disc diffusion method.
采用连续气-液绿色路线，在超声辐照下制备了具有不同壳聚糖包覆量的抗菌纳米束。将火花产生的气溶胶 Cu 纳米颗粒直接注入超声 Ag（I）-壳聚糖反应池，实现了 Cu 颗粒的高效水合以及随后的 Ag 和壳聚糖在 Cu 上的掺入。随后，采用静电喷雾法形成壳聚糖包覆的 Cu-Ag 纳米束涂层。当纳米束浓度从 10μgmL(-1)增加到 90μgmL(-1)时，将细菌增殖抑制到 50%所需的时间从 Ag（I）反应时间 2.0min 进一步缩短至~0.5h。通过使用静电喷涂设备将纳米束直接涂覆到基底上，制备了透明薄膜和复合纤维。然后通过圆盘扩散法评估了复合碳纤维的抗菌活性。
