Morsi Rania E, Alsabagh Ahmed M, Nasr Shimaa A, Zaki Manal M
Egyptian Petroleum Research Institute, Nasr City, Cairo P.B. 11727, Egypt.
Egyptian Petroleum Research Institute, Nasr City, Cairo P.B. 11727, Egypt.
Int J Biol Macromol. 2017 Apr;97:264-269. doi: 10.1016/j.ijbiomac.2017.01.032. Epub 2017 Jan 9.
Multifunctional nanocomposites of chitosan with silver nanoparticles, copper nanoparticles and carbon nanotubes either as bi- or multifunctional nanocomposites were prepared. Change in the overall morphology of the prepared nanocomposites was observed; carbon nanotubes, Ag NPs and Cu NPs are distributed homogeneously inside the polymer matrix individually in the case of the bi-nanocomposites while a combination of different dimensional shapes; spherical NPs and nanotubes was observed in the multifunctional nanocomposite. Multifunctional nanocomposites has a higher antimicrobial activity, in relative short contact times, against both Gram negative and Gram positive bacteria; E. coli, Staphylococcus aureus; respectively in addition to the fungal strain; Aspergillus flavus isolated from local wastewater sample. The nanocomposites are highly differentiable at the low contact time and low concentration; 1% concentration of the multifunctional nanocomposite is very effective against the tested microbes at contact time of only 10min.
制备了壳聚糖与银纳米颗粒、铜纳米颗粒和碳纳米管的多功能纳米复合材料，它们既可以是双功能纳米复合材料，也可以是多功能纳米复合材料。观察到所制备纳米复合材料的整体形态发生了变化；在双功能纳米复合材料中，碳纳米管、银纳米颗粒和铜纳米颗粒分别均匀分布在聚合物基质内部，而在多功能纳米复合材料中观察到不同尺寸形状的组合，即球形纳米颗粒和纳米管。多功能纳米复合材料在相对较短的接触时间内，对革兰氏阴性菌和革兰氏阳性菌，分别为大肠杆菌、金黄色葡萄球菌，以及从当地废水样品中分离出的真菌菌株黄曲霉，均具有较高的抗菌活性。这些纳米复合材料在低接触时间和低浓度下具有高度的可区分性；仅10分钟的接触时间，1%浓度的多功能纳米复合材料对受试微生物就非常有效。
