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多节段皮质骨轨迹螺钉在老年成人退变性脊柱侧凸伴狭窄中的安全性和有效性:至少5年随访研究

The Safety and Effectiveness of Multi-Segment Cortical Bone Trajectory Screws in Adult Degenerative Scoliosis with Stenosis Among the Elderly: Minimum 5-year Follow-up Study.

作者信息

Wang Jie, Ding Zihao, Liu Yuzeng, Hai Yong

机构信息

Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, People's Republic of China.

Joint Laboratory for Research & Treatment of Spinal Cord Injury in Spinal Deformity, Capital Medical University, Beijing, 100069, People's Republic of China.

出版信息

Clin Interv Aging. 2025 Jul 28;20:1125-1135. doi: 10.2147/CIA.S527306. eCollection 2025.

Abstract

PURPOSE

To evaluate the long-term efficacy and safety of multi-segment cortical bone trajectory screws for treating mild adult degenerative scoliosis with stenosis among the elderly.

PATIENTS AND METHODS

From January 2018 to December 2019, a total of 41 patients of mild adult degenerative scoliosis with stenosis underwent posterior lumbar decompression, bone graft fusion, and internal fixation, which were retrospectively divided into pedicle screw (PS) group and cortical bone trajectory (CBT) screw group according to different internal fixation methods. The operation time, intraoperative blood loss, immobilization, and length of hospital stay were compared between the two groups. The visual analog score (VAS) of low back and leg pain, Oswestry disability index (ODI), Cobb angle, lumbar lordosis (LL) angle, apex vertebral translation (AVT), coronal balance distance (CBD) and sagittal vertical axis (SVA) were compared between the two groups preoperatively and 6 months, 1 year, 5 years postoperatively. Perioperative and follow-up complications were observed.

RESULTS

The CBT group was superior to PS group in operation time, intraoperative blood loss, immobilization, length of hospital stay (<0.05). The low back VAS and ODI in CBT group were significantly lower than those in PS group at 6 months, 1 year and 5 years postoperatively (<0.05). The leg VAS in CBT group was lower than PS group at 5 years postoperatively (<0.05). The incidence of screw loosening and adjacent segment disease 5 years postoperatively in CBT group was significantly lower than that in PS group (<0.05).

CONCLUSION

Multi-segment cortical bone trajectory screws is a safe and effective treatment option for mild adult degenerative scoliosis with stenosis among the elderly. This technique features miniinvasive trauma and quick recovery, which might lead to improved long-term quality of life and a reduction in screw loosening and adjacent segment disease rates.

摘要

目的

评估多节段皮质骨轨迹螺钉治疗老年成人轻度退变性脊柱侧凸伴椎管狭窄的长期疗效及安全性。

患者与方法

2018年1月至2019年12月,共有41例轻度成人退变性脊柱侧凸伴椎管狭窄患者接受了后路腰椎减压、植骨融合及内固定手术,根据不同内固定方法将其回顾性分为椎弓根螺钉(PS)组和皮质骨轨迹(CBT)螺钉组。比较两组的手术时间、术中出血量、制动时间及住院时间。比较两组术前、术后6个月、1年、5年时的腰腿痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、Cobb角、腰椎前凸(LL)角、顶椎平移(AVT)、冠状面平衡距离(CBD)和矢状面垂直轴(SVA)。观察围手术期及随访并发症。

结果

CBT组在手术时间、术中出血量、制动时间、住院时间方面均优于PS组(<0.05)。术后6个月、1年和5年时,CBT组的腰VAS和ODI均显著低于PS组(<0.05)。术后5年时,CBT组的腿VAS低于PS组(<0.05)。术后5年时,CBT组螺钉松动和邻近节段病变的发生率显著低于PS组(<0.05)。

结论

多节段皮质骨轨迹螺钉是治疗老年成人轻度退变性脊柱侧凸伴椎管狭窄的一种安全有效的治疗选择。该技术具有微创创伤和快速恢复的特点,可能会改善长期生活质量并降低螺钉松动和邻近节段病变的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/182c/12315861/a612f0a8fe74/CIA-20-1125-g0001.jpg

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