肝血不足证患者红细胞ATP酶活性及耗氧量的变化
Alterations of erythrocyte ATPase activity and oxygen consumption in patients with liver-blood deficiency syndrome.
作者信息
Shi L J, Liu J F, Zhang Z Q, Lu Y Q, Shu Y G, Chen G L, Xin Z H, Xu J Y
机构信息
Lin-Jie Shi, Zi-Qiang Zhang, Guo-Lin Chen, Zhi-Hua Xin, Institute of Integrated TCM and Western Medicine, Hunan Medical University, Changsha 410008, Hunan Province, China.
出版信息
World J Gastroenterol. 1997 Sep 15;3(3):180-1. doi: 10.3748/wjg.v3.i3.180.
AIM
To investigate the pathophysiology of erythrocyte energy metabolic changes of patients with the traditional Chinese Medicine (TCM) liver-blood deficiency syndrome (LBDS).
METHODS
Erythrocyte membrane ATPase activity and oxygen consumption rate (OCR) were determined in 66 patients with LBDS, including 35 patients with iron deficiency anemia and 31 patients with chronic aplastic anemia. Thirty healthy adults served as controls.
RESULTS
ATPase activity and OCR were decreased in patients with LBDS.
CONCLUSION
The decreased erythrocyte ATPase activity and OCR might cause the energy hypometabolism in LBDS patients.
目的
探讨中医肝血不足证患者红细胞能量代谢变化的病理生理学机制。
方法
测定66例肝血不足证患者的红细胞膜ATP酶活性和氧消耗率（OCR），其中包括35例缺铁性贫血患者和31例慢性再生障碍性贫血患者。30名健康成年人作为对照。
结果
肝血不足证患者的ATP酶活性和OCR降低。
结论
红细胞ATP酶活性和OCR降低可能导致肝血不足证患者能量代谢低下。
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