Foong Yi Chao, Chherawala Nabil, Aitken Dawn, Scott David, Winzenberg Tania, Jones Graeme
Menzies Institute for Medical Research University of Tasmania Private Bag 23 Hobart Tasmania 7000 Australia; North West Regional Hospital Burnie Tasmania 7250 Australia.
Menzies Institute for Medical Research University of Tasmania Private Bag 23 Hobart Tasmania 7000 Australia.
J Cachexia Sarcopenia Muscle. 2016 Jun;7(3):275-83. doi: 10.1002/jcsm.12065. Epub 2015 Oct 15.
The aim of this study was to describe the relationship between accelerometer-determined physical activity (PA), muscle mass, and lower-limb strength in community-dwelling older adults.
Six hundred thirty-six community-dwelling older adults (66 ± 7 years) were studied. Muscle mass was measured using dual-energy x-ray absorptiometry, whilst lower limb strength was measured via dynamometry. We measured minutes/day spent in sedentary, light, moderate, and vigorous intensity activity using Actigraph GT1M accelerometers.
Participants spent a median of 583(Interquartile ratio (IQR) 522-646), 225(176-271), 27(12-45) and 0(0-0) min in sedentary, light, moderate, and vigorous activity, respectively. PA intensity was positively associated with both lean mass percentage and lower limb strength in a dose-response fashion. Sedentary activity was negatively associated with lean mass percentage, but not lower-limb strength. There was a positive association between PA and appendicular lean mass in men only. There was an interaction between age and activity; as age increased, the magnitude of the association of PA with lean mass percentage decreased. Those who adhered to the Australian Department of Health PA guidelines (moderate/vigorous PA >/=150 min/week) had greater lean mass percentage, appendicular lean mass, and lower limb strength.
Using accelerometer technology, both the amount and intensity of accelerometer-determined PA had an independent, dose-response relationship with lean mass percentage and lower limb strength, with the largest effect for vigorous activity. Time spent in sedentary activity was negatively associated with lean mass percentage, but was not associated with lower limb strength. The magnitude of the association between PA and lean mass percentage decreased with age, suggesting that PA programmes may need to be modified with increasing age.
本研究旨在描述社区居住的老年人中，通过加速度计测定的身体活动（PA）、肌肉质量和下肢力量之间的关系。
对636名社区居住的老年人（66±7岁）进行了研究。使用双能X线吸收法测量肌肉质量，通过测力计测量下肢力量。我们使用Actigraph GT1M加速度计测量了每天久坐、轻度、中度和剧烈强度活动所花费的分钟数。
参与者在久坐、轻度、中度和剧烈活动中分别花费的中位数为583（四分位间距（IQR）522 - 646）、225（176 - 271）、27（12 - 45）和0（0 - 0）分钟。PA强度与瘦体重百分比和下肢力量均呈剂量反应关系的正相关。久坐活动与瘦体重百分比呈负相关，但与下肢力量无关。仅在男性中，PA与上肢瘦体重之间存在正相关。年龄与活动之间存在相互作用；随着年龄的增加，PA与瘦体重百分比的关联程度降低。那些遵循澳大利亚卫生部PA指南（中度/剧烈PA≥150分钟/周）的人具有更高的瘦体重百分比、上肢瘦体重和下肢力量。
使用加速度计技术，通过加速度计测定的PA的量和强度与瘦体重百分比和下肢力量均具有独立的剂量反应关系，对剧烈活动的影响最大。久坐活动所花费的时间与瘦体重百分比呈负相关，但与下肢力量无关。PA与瘦体重百分比之间的关联程度随年龄增加而降低，这表明PA计划可能需要随着年龄的增长而进行调整。
