Ademola Isaiah Oluwafemi
Department of Veterinary Microbiology and Parasitology,University of Ibadan,Ibadan,Nigeria.
Anim Health Res Rev. 2016 Dec;17(2):85-91. doi: 10.1017/S1466252316000049. Epub 2016 Jun 1.
Bioactive compounds from marine and terrestrial organisms have been used extensively in the treatment of many diseases in both their natural form and as templates for synthetic modifications. This review summarizes present knowledge about anthelmintic effects of the extracts of bioactive plants in Nigeria against helminth parasites of ruminants. Plants traditionally used in livestock production are discussed. The main focus is hinged on in vitro and in vivo activities of secondary plant metabolites against nematodes of livestock. This review provides insight into preliminary studies of medicinal plants, which can be investigated further to discover promising molecules in the search for novel anthelmintic drugs and nutraceuticals.
来自海洋和陆地生物的生物活性化合物,已以其天然形式以及作为合成修饰模板,广泛用于多种疾病的治疗。本综述总结了目前关于尼日利亚生物活性植物提取物对反刍动物蠕虫寄生虫驱虫作用的知识。讨论了传统上用于畜牧生产的植物。主要重点在于植物次生代谢产物对家畜线虫的体外和体内活性。本综述为药用植物的初步研究提供了见解,可进一步研究这些植物,以发现有前景的分子,用于寻找新型驱虫药物和营养保健品。