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评估一家三级医院的术后持续性疼痛:发病率、生活质量、相关因素及治疗

Evaluating Persistent Postoperative Pain in One Tertiary Hospital: Incidence, Quality of Life, Associated Factors, and Treatment.

作者信息

Guimaraes-Pereira Luis, Valdoleiros Ines, Reis Pedro, Abelha Fernando

机构信息

Department of Anesthesiology, Centro Hospitalar Sao Joao, Alameda Professor Hernani Monteiro, Oporto, Portugal.

Department of Anesthesiology, Centro Hospitalar Sao Joao, Alameda Professor Hernani Monteiro, Oporto, Portugal; Department of Surgery, Faculty of Medicine, Alameda Professor Hernani Monteiro, University of Porto, Oporto, Portugal.

出版信息

Anesth Pain Med. 2016 Mar 2;6(2):e36461. doi: 10.5812/aapm.36461. eCollection 2016 Apr.

Abstract

BACKGROUND

Persistent postoperative pain (PPP) is defined as persistent pain after surgery of greater than three months' duration.

OBJECTIVES

Identify the incidence of PPP in our hospital and its associated factors; evaluate quality of life (QoL) and treatment of patients.

PATIENTS AND METHODS

We conducted an observational prospective study in adults proposed to various types of surgery using the brief pain inventory short form preoperatively (T0), one day after surgery, and three months later (T3). If the patient had pain at T3 and other causes of pain were excluded, they were considered to have PPP, and the McGill Pain Questionnaire Short Form was applied. QoL was measured with the EuroQol 5-dimension questionnaire (EQ-5D).

RESULTS

One hundred seventy-five patients completed the study. The incidence of PPP was 28%, and the affected patients presented lower QoL. The majority referred to a moderate to severe level of interference in their general activity. Cholecystectomies were less associated with PPP, and total knee/hip replacements were more associated with it. Preoperative pain, preoperative benzodiazepines or antidepressants, and more severe acute postoperative pain were associated with the development of PPP. Half of the patients with PPP were under treatment, and they refer a mean symptomatic relief of 69%.

CONCLUSIONS

This study, apart from attempting to better characterize the problem of PPP, emphasizes the lack of its treatment.

摘要

背景

术后持续性疼痛(PPP)被定义为手术后持续超过三个月的疼痛。

目的

确定我院PPP的发生率及其相关因素;评估患者的生活质量(QoL)和治疗情况。

患者与方法

我们对拟接受各类手术的成年人进行了一项前瞻性观察研究,术前(T0)、术后一天及三个月后(T3)使用简明疼痛问卷简表。如果患者在T3时存在疼痛且排除了其他疼痛原因,则认为其患有PPP,并应用麦吉尔疼痛问卷简表。使用欧洲五维健康量表(EQ-5D)测量生活质量。

结果

175名患者完成了研究。PPP的发生率为28%,受影响患者的生活质量较低。大多数患者表示其日常活动受到中度至重度干扰。胆囊切除术与PPP的关联较小,全膝关节/髋关节置换术与PPP的关联较大。术前疼痛、术前使用苯二氮䓬类药物或抗抑郁药以及术后更严重的急性疼痛与PPP的发生有关。一半的PPP患者正在接受治疗,他们表示症状平均缓解了69%。

结论

本研究除了试图更好地描述PPP问题外,还强调了其治疗的不足。

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