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治疗术后长期疼痛的新方法:APS 门诊诊所。

New approach for treatment of prolonged postoperative pain: APS Out-Patient Clinic.

作者信息

Tiippana Elina, Hamunen Katri, Heiskanen Tarja, Nieminen Teija, Kalso Eija, Kontinen Vesa K

机构信息

Division of Anaesthesiology, Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Division of Pain Medicine, Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

出版信息

Scand J Pain. 2016 Jul;12:19-24. doi: 10.1016/j.sjpain.2016.02.008. Epub 2016 Mar 11.

Abstract

BACKGROUND AND AIMS

Persistent postoperative pain (PPP) is a significant clinical problem. Several patient-related risk factors for PPP have been identified, including a previous chronic pain problem, young age, female gender and psychological vulnerability. Intra- and postoperative risk factors include surgical complications such as infections, haematoma, nerve damage and repeated surgery. As the length of hospital stay has been shortened, some patients may be discharged despite ongoing pain and insufficient analgesic medication. The challenge is to identify patients at high risk of developing PPP and to create a targeted care pathway to ensure effective and safe pain treatment especially in the subacute postoperative phase at home. This observational study describes the first two years of the Acute Pain Service Out-Patient Clinic (APS-OPC) at the Helsinki University Hospital.

METHODS

Patient characteristics, known risk factors, and details of treatment of PPP for the first 200 patients referred to our APS-OPC were retrospectively collected from the medical records. The APS-OPC clinic functions in close collaboration with the Multidisciplinary Pain Clinic (MPC), and the number of patients in need of physiotherapist, psychologist or psychiatrist counselling was recorded, as well as the number of patients referred to the MPC for further PPP management.

RESULTS

Patients were referred to the APS-OPC from different surgical specialities, the two most common being thoracic and orthopaedic surgery. Seventy per cent of the patients (139/200) presented symptoms indicating neuropathic postsurgical pain. The patients had, on average, five risk factors for PPP. The median time from surgery to the first contact to the APS-OPC was two months, and the median duration of follow-up was 2.8 months (0-16 months). The median number of contacts with APS-OPC was 3 (range 1-14). Every fourth patient needed only one contact to the APS-OPC. Nineteen per cent of the patients had an appointment with the physiotherapist and 20% with a psychologist or psychiatrist. At discharge after surgery, 54% of the patients were using weak opioids, 32% strong opioids and 71% gabapentinoids; at discharge from the APS-OPC, these numbers were 20%, 6% and 43%, respectively. Twenty-two per cent of the patients were referred to the MPC for further pain management.

CONCLUSIONS

The APS-OPC provides a fluent fast-track method of ensuring effective multimodal analgesia in the subacute recovery phase after surgery. Even strong opioids can be safely used after discharge and then tapered off in close supervision of the APS-OPC anaesthesiologist. As the APS-OPC was implemented in close collaboration with the MPC, the multidisciplinary resources are easily available during the course of the APS-OPC treatment.

IMPLICATIONS

The first two years of the APS-OPC have shown that a significant number of surgical patients benefit from continuing active pain management after discharge from hospital. This fast-track service provides physician-supervised titration of analgesics to improve pain relief in the subacute phase. An important task of the APS-OPC is to ensure that strong opioids are not inappropriately continued after recovery. Another goal of the APS-OPC is to identify patients in need of multidisciplinary pain management services to prevent chronification.

摘要

背景与目的

术后持续性疼痛(PPP)是一个重大的临床问题。已确定了几个与患者相关的PPP风险因素,包括既往慢性疼痛问题、年轻、女性性别和心理易损性。术中及术后风险因素包括手术并发症,如感染、血肿、神经损伤和再次手术。由于住院时间缩短,一些患者尽管仍有疼痛且镇痛药物不足,仍可能出院。挑战在于识别有发生PPP高风险的患者,并创建有针对性的护理途径,以确保有效且安全的疼痛治疗,尤其是在术后在家的亚急性期。这项观察性研究描述了赫尔辛基大学医院急性疼痛服务门诊(APS - OPC)的头两年情况。

方法

从病历中回顾性收集转诊至我们APS - OPC的前200例患者的特征、已知风险因素及PPP治疗细节。APS - OPC门诊与多学科疼痛门诊(MPC)密切合作开展工作,记录需要物理治疗师、心理学家或精神科医生咨询的患者数量,以及转诊至MPC进行进一步PPP管理的患者数量。

结果

患者从不同外科专科转诊至APS - OPC,最常见的两个专科是胸外科和骨科手术。70%的患者(139/200)出现提示神经性术后疼痛的症状。患者平均有5个PPP风险因素。从手术到首次接触APS - OPC的中位时间为两个月,中位随访时间为2.8个月(0 - 16个月)。与APS - OPC接触的中位次数为3次(范围1 - 14次)。每四位患者中只有一位仅需与APS - OPC接触一次。19%的患者预约了物理治疗师,20%预约了心理学家或精神科医生。术后出院时,54%的患者使用弱阿片类药物,32%使用强阿片类药物,71%使用加巴喷丁类药物;从APS - OPC出院时,这些数字分别为20%、6%和43%。22%的患者被转诊至MPC进行进一步的疼痛管理。

结论

APS - OPC提供了一种流畅的快速通道方法,可确保术后亚急性期有效的多模式镇痛。即使是强阿片类药物在出院后也可安全使用,然后在APS - OPC麻醉医生的密切监督下逐渐减量。由于APS - OPC是与MPC密切合作实施的,在APS - OPC治疗过程中多学科资源很容易获取。

启示

APS - OPC的头两年表明,大量手术患者在出院后继续接受积极的疼痛管理中受益。这种快速通道服务提供医生监督下的镇痛药滴定,以改善亚急性期的疼痛缓解。APS - OPC的一项重要任务是确保康复后不会不恰当地继续使用强阿片类药物。APS - OPC的另一个目标是识别需要多学科疼痛管理服务的患者,以防止疼痛慢性化。

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