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系统性红斑狼疮中的干燥综合征:第一部分。系统性红斑狼疮患者中干燥综合征临床及亚临床特征的发生率

Sjogren's syndrome in SLE: Part I. The frequency of the clinical and subclinical features of Sjogren's syndrome in patients with SLE.

作者信息

Grennan D M, Ferguson M, Williamson J, Mavrikakis M, Dick W C, Buchanan W W

出版信息

N Z Med J. 1977 Oct 26;86(598):374-6.

PMID:272546
Abstract

Clinical features of Sjogren's syndrome were found in 31 percent of 32 patients with SLE. Eight patients had features of KCS while four had xerostomia. Subclinical abnormalities were found in six other patients tested with sialography and labial salivary gland biopsy and there were abnormalities in 65 percent of SLE patients in whom labial salivary gland biopsy was performed. The prevalence of Raynaud's phenomenon and renal disease in SLE patients with and without Sjogren's syndrome were similar but four of the five patients with SLE and an erosive arthritis had symptomatic Sjogren's syndrome.

摘要

在32例系统性红斑狼疮(SLE)患者中,31%出现了干燥综合征的临床特征。8例有角结膜干燥症表现,4例有口干症状。另外6例经唾液腺造影和唇唾液腺活检检测发现有亚临床异常,在进行唇唾液腺活检的SLE患者中,65%存在异常。有和没有干燥综合征的SLE患者中雷诺现象和肾脏疾病的患病率相似,但5例患有侵蚀性关节炎的SLE患者中有4例有症状性干燥综合征。

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