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用于医疗应用的聚醚醚酮(PEEK)。

Polyetheretherketone (PEEK) for medical applications.

作者信息

Panayotov Ivan Vladislavov, Orti Valérie, Cuisinier Frédéric, Yachouh Jacques

机构信息

Laboratoire de Bioingénierie et Nanosciences EA 4203, UFR Odontologie, Université de Montpellier, 545 Avenue du Professeur Jean-Louis Viala, 34193, Montpellier Cedex 5, France.

出版信息

J Mater Sci Mater Med. 2016 Jul;27(7):118. doi: 10.1007/s10856-016-5731-4. Epub 2016 Jun 3.

Abstract

Polyetheretherketone (PEEK) is a polyaromatic semi-crystalline thermoplastic polymer with mechanical properties favorable for bio-medical applications. Polyetheretherketone forms: PEEK-LT1, PEEK-LT2, and PEEK-LT3 have already been applied in different surgical fields: spine surgery, orthopedic surgery, maxillo-facial surgery etc. Synthesis of PEEK composites broadens the physicochemical and mechanical properties of PEEK materials. To improve their osteoinductive and antimicrobial capabilities, different types of functionalization of PEEK surfaces and changes in PEEK structure were proposed. PEEK based materials are becoming an important group of biomaterials used for bone and cartilage replacement as well as in a large number of diverse medical fields. The current paper describes the structural changes and the surface functionalization of PEEK materials and their most common biomedical applications. The possibility to use these materials in 3D printing process could increase the scientific interest and their future development as well.

摘要

聚醚醚酮(PEEK)是一种聚芳族半结晶热塑性聚合物,其机械性能有利于生物医学应用。聚醚醚酮的几种形式:PEEK-LT1、PEEK-LT2和PEEK-LT3已应用于不同的外科领域,如脊柱外科、矫形外科、颌面外科等。聚醚醚酮复合材料的合成拓宽了聚醚醚酮材料的物理化学和机械性能。为了提高其骨诱导和抗菌能力,人们提出了聚醚醚酮表面的不同功能化类型以及聚醚醚酮结构的改变。基于聚醚醚酮的材料正成为用于骨和软骨置换以及大量不同医学领域的重要生物材料组。本文描述了聚醚醚酮材料的结构变化、表面功能化及其最常见的生物医学应用。在3D打印过程中使用这些材料的可能性也可能增加科学兴趣及其未来发展。

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