Shamoon Rawand Pouls, Muhammed Nawsherwan Sadiq, Jaff Muhammed Salih
Khanzad Street Erbil - Iraq, Phone: +964 750 4498630 E-mail:
Turk J Haematol. 2009 Sep 5;26(3):123-8.
To determine prevalence and define causes of pregnancy associated thrombocytopenia
A total of 850 pregnant women at different ages of gestation were screened for thrombocytopenia. A control group of 150 age-matched nonpregnant women were tested for platelet count. Neoborns of thrombocytopenic women were tested within 24 hours of delivery and reassessment of women's platelets was done within 7-10 days post delivery.
The mean platelet count in pregnant women was significantly lower than in nonpregnant women (221±59.9 vs. 273±66.9). Thrombocytopenia affected 8% of cases, with peak incidence during the third trimester. Gestational thrombocytopenia was found to be the principal cause (73.8%); hypertensive disorders caused thrombocytopenia in 23% of cases and two cases (4%) were due to immune thrombocytopenic purpura. No maternal or fetal complications were noted. The mean platelet count of 51 neoborns of thrombocytopenic women was (240 ± 7.1). Two neoborns (4%) had low platelet counts.
Majority of thrombocytopenias were mild gestational and occurred in late in pregnancy. No maternal or neonatal bleeding complications were observed.
确定妊娠相关血小板减少症的患病率并明确其病因。
对850名不同孕周的孕妇进行血小板减少症筛查。选取150名年龄匹配的非孕妇作为对照组进行血小板计数检测。对血小板减少症孕妇的新生儿在出生后24小时内进行检测,并在产后7 - 10天对孕妇血小板进行重新评估。
孕妇的平均血小板计数显著低于非孕妇(221±59.9对273±66.9)。血小板减少症影响了8%的病例,在孕晚期发病率最高。妊娠期血小板减少症被发现是主要原因(73.8%);高血压疾病导致23%的病例出现血小板减少症,两例(4%)是由于免疫性血小板减少性紫癜。未观察到母婴并发症。血小板减少症孕妇的51名新生儿的平均血小板计数为(240±7.1)。两名新生儿(4%)血小板计数低。
大多数血小板减少症为轻度妊娠期血小板减少症,发生在妊娠晚期。未观察到母婴出血并发症。