Dey A C, Hossain M I, Afroze S, Dey S K, Mannan M A, Shahidullah M
Dr Arjun Chandra Dey, Assistant Professor, Department of Neonatology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail: acd_70@yahoo. Com.
Mymensingh Med J. 2016 Apr;25(2):243-7.
It was a survey type of cross sectional study where the participants were from different teaching/referral hospital across the country and was done to gather information regarding current practice of management of neonatal sepsis among paediatricians and neonatologists and was conducted on the spot during a national conference of Bangladesh Perinatal Society in December 2013. Specialists in neonatology, paediatrics, and some other disciplines working in different institutes across the country were requested to respond. Out of 150 physicians, 92 (61.33%) were neonatologists. Physicians suspected early onset neonatal sepsis (EONS) when there is history suggestive of prolonged rupture of membrane (74.77%), prolonged labour (9.33%), chorioamnionitis (7.33%) and maternal fever (2%). Clinical sepsis is found commonly (53.33%) which is later proved by laboratory evidences such as Hb%, TC, DC PBF (peripheral blood film), C-reactive protein, chest X-ray etc. Injection Ampicillin and Gentamycin are still the first choice of antibiotics (61.3%). Preferred route was intravenous (95.3%). Antibiotics were given for 7-10 days by most of the physicians (48.77%). However there is lack of uniformity among the participants in regard to taking decision about antibiotics, the choice of first line and the subsequent options of antibiotics. So, neonatal sepsis is the most important cause of neonatal mortality in the community. Therefore a standard protocolized approach for diagnosis and management of Early Onset Neonatal Sepsis may prove critical which is currently not in practice uniformly.
这是一项横断面调查研究，参与者来自全国不同的教学/转诊医院，旨在收集儿科医生和新生儿科医生对新生儿败血症当前管理实践的信息，该研究于2013年12月在孟加拉国围产期协会全国会议期间现场进行。要求全国不同机构工作的新生儿科、儿科和其他一些学科的专家做出回应。在150名医生中，92名（61.33%）是新生儿科医生。当有胎膜早破时间延长（74.77%）、产程延长（9.33%）、绒毛膜羊膜炎（7.33%）和母亲发热（2%）的病史时，医生怀疑为早发型新生儿败血症（EONS）。临床败血症很常见（53.33%），随后通过血红蛋白百分比、总胆固醇、白细胞分类、外周血涂片、C反应蛋白、胸部X线等实验室证据得到证实。氨苄西林和庆大霉素注射剂仍然是抗生素的首选（61.3%）。首选途径是静脉注射（95.3%）。大多数医生（48.77%）给予抗生素7至10天。然而，在抗生素决策、一线选择和后续抗生素选择方面，参与者之间缺乏一致性。因此，新生儿败血症是社区新生儿死亡的最重要原因。因此，一种标准化的早发型新生儿败血症诊断和管理方案可能至关重要，而目前该方案并未得到统一实施。
