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本文引用的文献

1
Horizon scanning for translational genomic research beyond bench to bedside.超越从实验室到临床的转化基因组研究的前沿领域扫描。
Genet Med. 2014 Jul;16(7):535-8. doi: 10.1038/gim.2013.184. Epub 2014 Jan 9.
2
Prioritizing genomic applications for action by level of evidence: a horizon-scanning method.按证据水平优先考虑基因组应用的行动：一种 horizon-scanning 方法。
Clin Pharmacol Ther. 2014 Apr;95(4):394-402. doi: 10.1038/clpt.2013.226. Epub 2014 Feb 19.
3
Charting a course for genomic medicine from base pairs to bedside.为基因组医学绘制从碱基对到床边的路线图。
Nature. 2011 Feb 10;470(7333):204-13. doi: 10.1038/nature09764.
4
The genomic applications in practice and prevention network.基因组学在实践与预防方面的应用网络。
Genet Med. 2009 Jul;11(7):488-94. doi: 10.1097/GIM.0b013e3181a551cc.
5
GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique.GAP筛选器：一种利用支持向量机技术在PubMed中筛选人类基因关联文献的自动工具。
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6
A navigator for human genome epidemiology.人类基因组流行病学导航工具。
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The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?基因组医学中的翻译研究连续统一体：我们如何加速将人类基因组发现合理整合到医疗保健和疾病预防中？
Genet Med. 2007 Oct;9(10):665-74. doi: 10.1097/GIM.0b013e31815699d0.

一个用于追踪基因组学对人群健康影响的知识库。

A knowledge base for tracking the impact of genomics on population health.

作者信息

Yu Wei, Gwinn Marta, Dotson W David, Green Ridgely Fisk, Clyne Mindy, Wulf Anja, Bowen Scott, Kolor Katherine, Khoury Muin J

机构信息

Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

McKing Consulting Corporation, Atlanta, Georgia, USA.

出版信息

Genet Med. 2016 Dec;18(12):1312-1314. doi: 10.1038/gim.2016.63. Epub 2016 Jun 9.

DOI:10.1038/gim.2016.63
PMID:27280867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5133140/
Abstract

PURPOSE

We created an online knowledge base (the Public Health Genomics Knowledge Base (PHGKB)) to provide systematically curated and updated information that bridges population-based research on genomics with clinical and public health applications.

METHODS

Weekly horizon scanning of a wide variety of online resources is used to retrieve relevant scientific publications, guidelines, and commentaries. After curation by domain experts, links are deposited into Web-based databases.

RESULTS

PHGKB currently consists of nine component databases. Users can search the entire knowledge base or search one or more component databases directly and choose options for customizing the display of their search results.

CONCLUSION

PHGKB offers researchers, policy makers, practitioners, and the general public a way to find information they need to understand the complicated landscape of genomics and population health.Genet Med 18 12, 1312-1314.

摘要

目的

我们创建了一个在线知识库（公共卫生基因组学知识库（PHGKB）），以提供经过系统整理和更新的信息，搭建基于人群的基因组学研究与临床及公共卫生应用之间的桥梁。

方法

通过每周对各种在线资源进行前沿扫描，检索相关科学出版物、指南和评论。经领域专家整理后，链接被存入基于网络的数据库。

结果

PHGKB目前由九个组件数据库组成。用户可以搜索整个知识库，或直接搜索一个或多个组件数据库，并选择自定义搜索结果显示的选项。

结论

PHGKB为研究人员、政策制定者、从业者和普通公众提供了一种途径，以找到他们理解基因组学和人群健康复杂领域所需的信息。《遗传医学》18卷12期，1312 - 1314页。