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40岁以下患者的膀胱癌

Bladder carcinoma in patients less than 40 years of age.

作者信息

Witjes J A, Debruyne F M

机构信息

Department of Urology, Radboud University Hospital, Nijmegen, The Netherlands.

出版信息

Urol Int. 1989;44(2):81-3. doi: 10.1159/000281475.

Abstract

Between March 1983 and March 1988 we registered and treated 49 patients with bladder cancer less than 40 years of age (7 patients less than 30 years of age). Hematuria was present in 40 cases (81.6%). 33 of the patients had a pTA tumor (67.3%). 47 patients had transitional carcinoma of the bladder, of which 21 (44.7%) showed hallmarks of aggressive behavior (muscle invasion, recurrences, associated severe epithelial atypia); all of these patients were between 31 and 39 years of age. 15 patients had a recurrence (30.6%), of which 3 showed progression (all between 31 and 39 years of age). This report supports the view that transitional cell carcinoma of the bladder is less aggressive in patients less than 30 years of age. We still advise however to do a full diagnostic workup in case of symptoms of bladder tumor, and to treat the patient according to the pathological classification, regardless of the age.

摘要

1983年3月至1988年3月期间,我们登记并治疗了49例年龄小于40岁的膀胱癌患者(7例年龄小于30岁)。40例(81.6%)出现血尿。33例患者患有pTA肿瘤(67.3%)。47例患者患有膀胱移行癌,其中21例(44.7%)表现出侵袭性行为特征(肌肉浸润、复发、相关严重上皮异型性);所有这些患者年龄在31至39岁之间。15例患者复发(30.6%),其中3例出现进展(均在31至39岁之间)。本报告支持以下观点:年龄小于30岁的患者中,膀胱移行细胞癌的侵袭性较低。然而,我们仍然建议,对于出现膀胱肿瘤症状的患者,应进行全面的诊断检查,并根据病理分类进行治疗,而不论年龄大小。

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