Al-Radaideh Ali M, Rababah Eman M
Department of Medical Imaging, Faculty of Allied Health Sciences, The Hashemite University, Zarqa, Jordan.
Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, The Hashemite University, Zarqa, Jordan.
Clin Imaging. 2016 Sep-Oct;40(5):987-96. doi: 10.1016/j.clinimag.2016.05.006. Epub 2016 May 26.
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's in elderly people. Different structural and functional neuroimaging methods play a great role in the early diagnosis of neurodegenerative diseases. This review discusses the role of magnetic resonance imaging (MRI) in the diagnosis of PD. MRI provides clinicians with structural and functional information of human brain noninvasively. Advanced quantitative MRI techniques have shown promise for detecting pathological changes related to different stages of PD. Collectively, advanced MRI techniques at high and ultrahigh magnetic fields aid in better understanding of the nature and progression of PD.
帕金森病(PD)是老年人中仅次于阿尔茨海默病的第二常见神经退行性疾病。不同的结构和功能神经影像学方法在神经退行性疾病的早期诊断中发挥着重要作用。本综述讨论了磁共振成像(MRI)在帕金森病诊断中的作用。MRI为临床医生提供人脑的结构和功能信息,且无需侵入性操作。先进的定量MRI技术在检测与帕金森病不同阶段相关的病理变化方面显示出前景。总的来说,高场和超高场的先进MRI技术有助于更好地理解帕金森病的本质和进展。