在夸祖鲁-纳塔尔资源有限的环境中，感染人类免疫缺陷病毒-1 的儿童中，南非扩大乙型肝炎免疫规划的效果。
Effectiveness of the South African expanded program of immunization against hepatitis B in children infected with human immunodeficiency virus-1 living in a resource-limited setting of Kwazulu-Natal.
机构信息
AIDS Reference Laboratory, Saint-Luc University Hospital, Catholic University of Louvain, Brussels, Belgium.
AIDS Reference Laboratory, Catholic University of Louvain, Brussels, Belgium.
出版信息
J Med Virol. 2017 Jan;89(1):182-185. doi: 10.1002/jmv.24598. Epub 2016 Jun 24.
Prevalence of Human-Immunodeficiency-Virus/Hepatitis-B-virus (HIV/HBV) coinfection and HBV vaccination response in children are unknown in Kwazulu-Natal. This study included 183 HIV-infected and 108 HIV-uninfected children aged between 5 and 15 years screened for HBV infection and vaccination. HBV infection occurred in 2.1% and 0% of HIV-infected and uninfected children respectively. Serological response to immunization was shown in 15.8% and 61.1% of HIV-infected and uninfected children, respectively (P < 0.001). Even if prevalence of HBV infection was low in these cohorts, HIV-infected children will stay at risk of infection if the vaccine schedule is not adapted. J. Med. Virol. 89:182-185, 2017. © 2016 Wiley Periodicals, Inc.
在夸祖鲁-纳塔尔省，人们对儿童中的人类免疫缺陷病毒/乙型肝炎病毒（HIV/HBV）合并感染以及乙型肝炎病毒（HBV）疫苗接种反应的流行情况并不了解。本研究纳入了 183 名 HIV 感染者和 108 名 HIV 未感染者，他们的年龄在 5 至 15 岁之间，研究目的是筛查乙型肝炎病毒感染和疫苗接种情况。HBV 感染分别发生在 2.1%的 HIV 感染者和 0%的 HIV 未感染者中。免疫接种后的血清学反应分别显示在 15.8%的 HIV 感染者和 61.1%的 HIV 未感染者中（P < 0.001）。即使在这些队列中 HBV 感染的流行率较低，如果不调整疫苗接种计划，HIV 感染者仍将面临感染风险。医学病毒学杂志 89：182-185，2017. © 2016 威利父子出版公司
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