da Silva Ana Paula Fernandes, Mello Luciano de Albuquerque, Dos Santos Erlene Roberta Ribeiro, Paz Silvania Tavares, Cavalcanti Carmelita Lima Bezerra, de Melo-Junior Mario Ribeiro
Programa de Pós-Graduação em Patologia, Universidade Federal de Pernambuco (UFPE), Campus Universitário, Avenida Morais Rego s/n, Cidade Universitária, 50670-910 Recife, PE, Brazil; Laboratório de Imunopatologia Keizo Asami (LIKA), UFPE, Recife, PE, Brazil.
Laboratório de Imunopatologia Keizo Asami (LIKA), UFPE, Recife, PE, Brazil.
Obstet Gynecol Int. 2016;2016:2968410. doi: 10.1155/2016/2968410. Epub 2016 May 15.
The current study aims to evaluate histopathological and digital morphometrical aspects associated with uterine leiomyomas in one hundred and fifty (150) patients diagnosed with leiomyoma. Uterine tissues were subjected to the histopathological and digital morphometric analyses of the interstitial collagen distribution. The analysis of medical records indicates that most of the women diagnosed with uterine leiomyomas (68.7%) are between 37 and 48 years old. As for the anatomic location of the tumors, approximately 61.4% of the patients had intramural and subserosal lesions. In 50% of the studied cases, the patients developed uterine leiomyomatosis (with more than eight tumors). As for the morphometric study, the average size of the interstitial collagen distribution held approximately 28.53% of the capture area, whereas it was of 7.43% in the normal tissue adjacent to the tumor. Another important aspect observed in the current study was the high rate of young women subjected to total hysterectomy, a fact that resulted in early and definitive sterility.
本研究旨在评估150例诊断为平滑肌瘤的患者子宫平滑肌瘤的组织病理学和数字形态学特征。对子宫组织进行间质胶原分布的组织病理学和数字形态学分析。病历分析表明，大多数诊断为子宫平滑肌瘤的女性（68.7%）年龄在37至48岁之间。至于肿瘤的解剖位置，约61.4%的患者有肌壁间和浆膜下病变。在50%的研究病例中，患者发生了子宫平滑肌瘤病（有八个以上肿瘤）。至于形态学研究，间质胶原分布的平均大小约占捕获区域的28.53%，而在肿瘤相邻的正常组织中为7.43%。本研究中观察到的另一个重要方面是接受全子宫切除术的年轻女性比例很高，这一事实导致了早期和永久性不育。
