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肝病中的骨质疏松症:发病机制与管理

Osteoporosis in liver disease: pathogenesis and management.

作者信息

Handzlik-Orlik Gabriela, Holecki Michał, Wilczyński Krzysztof, Duława Jan

机构信息

Department of Internal Medicine and Metabolic Diseases, Medical University of Silesia, ul. Ziołowa 45/47, 40-635 Katowice, Poland.

Department of Internal Medicine and Metabolic Diseases, School of Health Science, Medical University of Silesia, Katowice, Poland.

出版信息

Ther Adv Endocrinol Metab. 2016 Jun;7(3):128-35. doi: 10.1177/2042018816641351. Epub 2016 Apr 6.

Abstract

Osteoporosis affects a substantial proportion of patients with chronic liver disease. Pathologic fracture in osteoporosis significantly affects quality of life and life expectancy. By some estimates, 40% of patients with chronic liver disease may experience osteoporotic fracture. In this study we review the pathogenesis, diagnosis and treatment of specific liver disease entities and their relation to osteoporosis.

摘要

骨质疏松症影响着相当一部分慢性肝病患者。骨质疏松症中的病理性骨折会显著影响生活质量和预期寿命。据一些估计,40%的慢性肝病患者可能会发生骨质疏松性骨折。在本研究中,我们回顾了特定肝病实体的发病机制、诊断和治疗及其与骨质疏松症的关系。

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本文引用的文献

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New method for point-of-care osteoporosis screening and diagnostics.即时护理骨质疏松症筛查与诊断的新方法。
Osteoporos Int. 2016 Mar;27(3):971-977. doi: 10.1007/s00198-015-3387-4. Epub 2015 Nov 10.
2
EASL Clinical Practice Guidelines: Autoimmune hepatitis.欧洲肝脏研究学会临床实践指南:自身免疫性肝炎
J Hepatol. 2015 Oct;63(4):971-1004. doi: 10.1016/j.jhep.2015.06.030. Epub 2015 Sep 1.
5
Osteoporosis in primary biliary cirrhosis of the liver.肝原发性胆汁性肝硬化中的骨质疏松症。
Prz Gastroenterol. 2014;9(2):82-7. doi: 10.5114/pg.2014.42502. Epub 2014 May 5.
8
Alcoholic liver disease and changes in bone mineral density.酒精性肝病与骨密度变化
Rev Esp Enferm Dig. 2013 Nov-Dec;105(10):609-21. doi: 10.4321/s1130-01082013001000006.
10
Extrahepatic complications of nonalcoholic fatty liver disease.非酒精性脂肪性肝病的肝外并发症。
Hepatology. 2014 Mar;59(3):1174-97. doi: 10.1002/hep.26717. Epub 2014 Jan 16.

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