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复发性颈动脉狭窄。自体静脉置换切除术。

Recurrent carotid artery stenosis. Resection with autogenous vein replacement.

作者信息

Edwards W H, Edwards W H, Mulherin J L, Martin R S

机构信息

Surgical Service, St. Thomas Hospital, Nashville, Tennessee.

出版信息

Ann Surg. 1989 Jun;209(6):662-8; discussion 668-9. doi: 10.1097/00000658-198906000-00002.

Abstract

Recurrent carotid artery stenosis (RCAS) occurs in 10% to 15% of patients following carotid endarterectomy (CEA). A recurrent stenosis may occur as early as 6 months and will become symptomatic in 3% to 5% of patients. Early stenosis is myointimal hyperplasia, but with the passage of time may progress to the characteristic atherosclerotic lesion. Improvements in noninvasive testing allows for evaluation and early detection of restenosis. Since 1974 we have performed 3711 CEAs in 2909 patients. One hundred and six second or third CEAs were performed in 98 patients (3.5%). In 20 of these reoperations, the common carotid (CCA) and internal carotid artery (ICA) were resected and replaced by autogenous vein, usually saphenous. One of these patients had 3 previous CEAs while 7 patients had 2 and 12 patients had 1 previous operation. There were no deaths; thrombosis of one vein interposition requiring replacement occurred. Hoarseness and hypoglossal nerve palsy occurred in one patient. Follow-up ranged to 5 years with a mean of 2.8 years. Although a second CEA is possible, there are inherent technical difficulties that may be encountered and vein interposition will solve these as well as offer the potential to prevent a further recurrence.

摘要

复发性颈动脉狭窄(RCAS)发生在颈动脉内膜切除术(CEA)后10%至15%的患者中。复发性狭窄最早可在6个月时出现,3%至5%的患者会出现症状。早期狭窄是肌内膜增生,但随着时间的推移可能会发展为典型的动脉粥样硬化病变。无创检测技术的进步有助于评估和早期发现再狭窄。自1974年以来,我们对2909例患者进行了3711次CEA。98例患者(3.5%)接受了106次二次或三次CEA。在其中20例再次手术中,切除了颈总动脉(CCA)和颈内动脉(ICA),并用自体静脉(通常是大隐静脉)进行了置换。这些患者中有1例曾接受过3次CEA,7例曾接受过2次,12例曾接受过1次手术。无死亡病例;发生了1例静脉搭桥血栓形成,需要进行置换。1例患者出现声音嘶哑和舌下神经麻痹。随访时间长达5年,平均为2.8年。虽然二次CEA是可行的,但可能会遇到一些固有的技术困难,而静脉搭桥既能解决这些问题,又有可能防止进一步复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391d/1494106/c82aac0779ab/annsurg00184-0019-a.jpg

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