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吸入“除尘宝”后出现的严重心肌病。

Severe Cardiomyopathy after Huffing Dust-Off™.

作者信息

Cates Alexis L, Cook Matthew D

机构信息

William Carey University College of Osteopathic Medicine, Hattiesburg, MS 39401, USA.

Department of Emergency Medicine, Lehigh Valley Hospital and Health Network/USF MCOM, Allentown, PA 18017, USA.

出版信息

Case Rep Emerg Med. 2016;2016:9204790. doi: 10.1155/2016/9204790. Epub 2016 May 25.

DOI:10.1155/2016/9204790
PMID:27313914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4897681/
Abstract

A 34-year-old man was found down in a parking lot after huffing fifteen cans of Dust-Off. Though lucid during the initial hospital evaluation, the patient experienced a generalized seizure followed by a torsades de pointes arrhythmia and was resuscitated. An echocardiogram revealed left and right ventricular dysfunction with an ejection fraction of 25%. This unique outcome of inhalant abuse has scarcely been reported in similar cases. The patient fully recovered and had a normal ejection fraction prior to discharge.

摘要

一名34岁男子在吸入15罐除尘剂后被发现倒在停车场。尽管在最初的医院评估中神志清醒,但该患者随后出现全身性癫痫发作,接着是尖端扭转型室性心动过速心律失常,并接受了复苏。超声心动图显示左、右心室功能障碍,射血分数为25%。这种吸入性药物滥用的独特结果在类似病例中鲜有报道。患者在出院前完全康复,射血分数正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ae/4897681/53817e6bdd32/CRIEM2016-9204790.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ae/4897681/ba505b2cd14b/CRIEM2016-9204790.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ae/4897681/53817e6bdd32/CRIEM2016-9204790.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ae/4897681/ba505b2cd14b/CRIEM2016-9204790.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ae/4897681/53817e6bdd32/CRIEM2016-9204790.002.jpg

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Fatal cardiac arrhythmia after repeated exposure to 1,1-difluoroethane (DFE).反复接触1,1 - 二氟乙烷(DFE)后出现致命性心律失常。
Am J Forensic Med Pathol. 2006 Mar;27(1):58-60. doi: 10.1097/01.paf.0000202715.71009.0e.
World J Cardiol. 2021 Oct 26;13(10):593-598. doi: 10.4330/wjc.v13.i10.593.
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Acute Refractory Hypocalcemia in a 51-Year-Old Male With a History of 1,1-Difluoroethane Inhalation.一名有1,1 - 二氟乙烷吸入史的51岁男性的急性难治性低钙血症
Cureus. 2021 Mar 4;13(3):e13693. doi: 10.7759/cureus.13693.
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1,1-Difluoroethane Detection Time in Blood after Inhalation Abuse Estimated by Monte Carlo PBPK Modeling.通过蒙特卡洛生理药代动力学(PBPK)模型估算吸入滥用后血液中1,1-二氟乙烷的检测时间。
Pharmaceutics. 2020 Oct 20;12(10):997. doi: 10.3390/pharmaceutics12100997.
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