气单胞菌感染后的慢性结肠炎。
Chronic colitis after Aeromonas infection.
作者信息
Willoughby J M, Rahman A F, Gregory M M
机构信息
Department of Medicine, Lister Hospital, Stevenage, Hertfordshire.
出版信息
Gut. 1989 May;30(5):686-90. doi: 10.1136/gut.30.5.686.
Three patients with an acute colitis in which the only pathogen detected was either Aeromonas hydrophila or A sobria progressed to a chronic phase after the infection had been eliminated by antibiotic treatment in two and had resolved spontaneously in the third. The final diagnosis in each case was ulcerative colitis. Two of the patients have responded to anti-inflammatory medication but one has required panproctocolectomy. The sequence of symptoms and observations in these cases, as well as in others from the literature involving more familiar pathogens, suggests that bacterial infection may contribute to the development of chronic colitis. This supposition could be tested by extending the follow up of patients with acute infective colitis in a prospective multicentre trial.
三名患有急性结肠炎的患者，其中仅检测到嗜水气单胞菌或温和气单胞菌这两种病原体。在两名患者中，感染通过抗生素治疗消除后进入了慢性期，而第三名患者的感染则自行消退。每例患者的最终诊断均为溃疡性结肠炎。其中两名患者对抗炎药物有反应，但有一名患者需要进行全直肠结肠切除术。这些病例以及文献中其他涉及更常见病原体的病例的症状和观察结果序列表明，细菌感染可能促成慢性结肠炎的发展。这一假设可以通过在前瞻性多中心试验中延长急性感染性结肠炎患者的随访来进行验证。
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