Janda J M
Microbial Diseases Laboratory, California Department of Health Services, Berkeley 94704-1011.
Clin Microbiol Rev. 1991 Oct;4(4):397-410. doi: 10.1128/CMR.4.4.397.
Over the past decade, the emergence of Aeromonas species as bona fide human pathogens and their probable role as etiologic agents of bacterial gastroenteritis have resulted in an explosion of scientific interest in the genus. Major accomplishments occurring in this field during that interval include a more refined taxonomy, identification of new cell-associated factors (surface layers, pili), and the molecular analysis of selected extracellular gene products that may play a critical role in pathogenesis (hemolysins, enterotoxins). This review provides an updated overview of recent systematic, clinical, and pathophysiologic advances and defines key areas of medical and scientific interest in which major questions remain unanswered.
在过去十年中，气单胞菌属作为真正的人类病原体出现，以及它们作为细菌性肠胃炎病原体的可能作用，引发了科学界对该属的极大兴趣。在此期间，该领域取得的主要成就包括更精细的分类学、新的细胞相关因子（表层、菌毛）的鉴定，以及对可能在发病机制中起关键作用的特定细胞外基因产物（溶血素、肠毒素）的分子分析。本综述提供了近期系统、临床和病理生理学进展的最新概述，并确定了医学和科学感兴趣的关键领域，其中主要问题仍未得到解答。
