Rao Theertham Pradyumna
Taiyo Kagaku Co Ltd, 800 Yamada-cho, Yokkaichi, Japan.
Physiol Behav. 2016 Oct 1;164(Pt A):277-83. doi: 10.1016/j.physbeh.2016.06.014. Epub 2016 Jun 15.
Appetite control and reduction of additional calorie intake may be a logical approach for proper weight management. Viscous dietary fibers are effective in appetite control but difficult to apply in normal serving sizes in foods and nutritional supplements due to their viscosity and required high doses. Guar fiber popularly known as partially hydrolyzed guar gum (PHGG) is near non-viscous soluble fiber that has been proven effective in providing many physiological benefits. Guar fiber has also been identified as potential natural food and nutritional supplement ingredient for appetite control. The aim of this review is to summarize all the clinical studies pertinent to its effects on appetite control in normal subjects and postulate the mechanism of action. Guar fiber exhibited appetite control via delaying the colonic transit time of digested food, stimulation of satiety hormone cholecystokinin (CCK) and induction of prolonged perception of post-meal satiation and satiety effects. Regular intake of guar fiber at a dose of 2g/serving provided significant sustained post-meal satiation effects and minimized the inter-meal calorie intake by about 20% in normal subjects. The intake of guar fiber alone at a dose >5g/serving or its combination with protein (2.6g guar fiber+8g protein/serving) showed acute satiety effects in normal subjects. Guar fiber containing >85% dietary fiber, with clear solubility and negligible taste impact, may be an ideal natural dietary fiber for use in food and supplement applications at low dosage levels for appetite control.
控制食欲和减少额外热量摄入可能是合理体重管理的一种合乎逻辑的方法。粘性膳食纤维在控制食欲方面有效,但由于其粘性和所需的高剂量,难以以正常食用量应用于食品和营养补充剂中。瓜尔豆纤维通常被称为部分水解瓜尔胶(PHGG),是一种几乎无粘性的可溶性纤维,已被证明在提供许多生理益处方面有效。瓜尔豆纤维也被确定为控制食欲的潜在天然食品和营养补充剂成分。本综述的目的是总结所有与正常受试者食欲控制作用相关的临床研究,并推测其作用机制。瓜尔豆纤维通过延迟消化食物的结肠转运时间、刺激饱腹感激素胆囊收缩素(CCK)以及诱导餐后饱腹感和饱腹感的长期感知来控制食欲。正常受试者以每餐2克的剂量定期摄入瓜尔豆纤维可提供显著的持续餐后饱腹感,并将餐间热量摄入减少约20%。单独以每餐>5克的剂量摄入瓜尔豆纤维或其与蛋白质(2.6克瓜尔豆纤维+8克蛋白质/餐)的组合在正常受试者中显示出急性饱腹感作用。瓜尔豆纤维含有>85%的膳食纤维,具有明显的溶解性且味觉影响可忽略不计,可能是一种理想的天然膳食纤维,可在低剂量水平用于食品和补充剂应用中以控制食欲。