小梁切开联合丝裂霉素C的粘小管成形术治疗原发性先天性青光眼
Viscocanalostomy combined with trabeculotomy and mitomycin C in the treatment of primary congenital glaucoma.
作者信息
Qian Chao-Xu, Zong Yuan, Chen Qin, Yuan Zhi-Lan
机构信息
Department of Ophthalmology, the Third People's Hospital of Changzhou, Changzhou 213001, Jiangsu Province, China.
Department of Ophthalmology, Eye, Ear, Nose & Throat Hospital of Fudan University, Shanghai 200031, China.
出版信息
Int J Ophthalmol. 2017 Jun 18;10(6):919-924. doi: 10.18240/ijo.2017.06.14. eCollection 2017.
AIM
To evaluate the long-term outcome of viscocanalostomy combined with trabeculotomy and mitomycin C in the treatment of primary congenital glaucoma.
METHODS
This is a retrospective study. Forty-two eyes of 26 patients with primary congenital glaucoma were enrolled. Intraocular pressure (IOP), corneal diameter (mm) and cup/disc (C/D) were measured before and after the surgery respectively. Follow-up period was 30mo.
RESULTS
The mean preoperative IOP was 30.6±7.35 mm Hg. Of the 42 eyes, 2 eyes were required conversion to trabeculectomy for the absence of Schlemm's canal. Of remained 40 eyes, 38 eyes (95%) achieved successful IOP control. The average postoperative IOP was 11.69±4.18 mm Hg at 12mo. The mean reduction was 18.91 mm Hg (<0.0001). Eighteen (75%) eyes presented a reduction in corneal diameter, and 25 (62.5%) eyes presented a C/D ratio reversal after the surgery. There was no serious complication in any patients over the follow-up period.
CONCLUSION
Viscocanalostomy combined with trabeculotomy and mitomycin C is useful in the management of primary congenital glaucoma.
目的
评估粘小管切开术联合小梁切开术及丝裂霉素C治疗原发性先天性青光眼的长期疗效。
方法
这是一项回顾性研究。纳入26例原发性先天性青光眼患者的42只眼。分别在手术前后测量眼压（IOP）、角膜直径（mm）及杯盘比（C/D）。随访期为30个月。
结果
术前平均眼压为30.6±7.35 mmHg。42只眼中，2只眼因未找到施莱姆管而改行小梁切除术。其余40只眼中，38只眼（95%）眼压控制成功。术后12个月平均眼压为11.69±4.18 mmHg。平均降低18.91 mmHg（<0.0001）。18只眼（75%）术后角膜直径缩小，25只眼（62.5%）术后杯盘比逆转。随访期间所有患者均无严重并发症。
结论
粘小管切开术联合小梁切开术及丝裂霉素C对原发性先天性青光眼的治疗有效。
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