Cristiano P, Iovene M R, Morelli G, Mandia L, Paradisi F, Altucci P
Institute of Internal Medicine, 1st Medical School, Naples University, Italy.
J Chemother. 1989 Apr;1(2):107-9. doi: 10.1080/1120009x.1989.11738875.
Thirty-four hospitalized patients with various infections: 19 with typhoid fever, 4 with gastroenteritis, 7 with lower respiratory tract infections, 2 with biliary tract infections, 1 with brucellosis and 1 with infection of necrotic ulceration of the feet, were treated with ofloxacin at a daily dosage ranging between 600 and 900 mg orally. Thirty-one of 34 patients (91.18%) completely recovered and pathogens were eradicated. In 2 patients, both with respiratory tract infections, the treatment failed and in one patient, affected by infection of necrotic ulcerations of the feet, improvement was registered. No side effects were recorded. Ofloxacin can be considered a safe and effective antimicrobial agent in the therapy of these infections.
34例住院的各种感染患者：19例患伤寒热，4例患肠胃炎，7例患下呼吸道感染，2例患胆道感染，1例患布鲁氏菌病，1例患足部坏死性溃疡感染，口服氧氟沙星，日剂量在600至900毫克之间。34例患者中有31例（91.18%）完全康复，病原体被根除。2例均为呼吸道感染的患者治疗失败，1例足部坏死性溃疡感染患者病情有改善。未记录到副作用。氧氟沙星可被认为是治疗这些感染的一种安全有效的抗菌药物。
