玻璃体内注射后视网膜裂孔和孔源性视网膜脱离：其患病率及病例报告
Retinal tears and rhegmatogenous retinal detachment after intravitreal injections: its prevalence and case reports.
作者信息
Karabag Revan Yildirim, Parlak Melih, Cetin Gölgem, Yaman Aylin, Osman Saatci A
机构信息
Department of Ophthalmology, Dokuz Eylul University Medical School, Izmir, Turkey;
Department of Ophthalmology, Klinikum Konstanz, Konstanz, Germany.
出版信息
Digit J Ophthalmol. 2015 Mar 23;21(1):8-10. doi: 10.5693/djo.01.2014.07.001. eCollection 2015.
PURPOSE
To report the prevalence of postoperative retinal tear or rhegmatogenous retinal detachment secondary to intravitreal injections.
METHODS
Surgical and medical records of patients who received intravitreal injections at the practice of a single retina specialist from January 2004 to May 2013 and who were followed for at least 6 months were investigated retrospectively.
RESULTS
During the study period, a total of 3,907 intravitreal injections were performed in 1,049 eyes of 784 patients (416 males [47%]). The mean number of injections per eye was 3.72 ± 3.43 (range, 1-22). The mean age of the participants was 67.03 ± 13.56 (range, 5-94 years). The mean follow-up time was 31.98 ± 22.86 months (range, 6-144 months). Retinal break or rhegmatogenous retinal detachment occurred in 3 injections of 3 eyes, yielding an overall prevalence of 0.077% per injection and 0.29% per eye.
CONCLUSIONS
Retinal tear and rhegmatogenous detachment are rare complications of intravitreal injection. Precautions should be taken especially in patients having predisposing conditions, such as high myopia, or any other vitreoretinal disorders.
目的
报告玻璃体内注射继发的术后视网膜裂孔或孔源性视网膜脱离的患病率。
方法
回顾性调查2004年1月至2013年5月在一名视网膜专科医生处接受玻璃体内注射且随访至少6个月的患者的手术和医疗记录。
结果
在研究期间，共对784例患者（416例男性[47%]）的1049只眼进行了3907次玻璃体内注射。每只眼的平均注射次数为3.72±3.43（范围1 - 22次）。参与者的平均年龄为67.03±13.56（范围5 - 94岁）。平均随访时间为31.98±22.86个月（范围6 - 144个月）。3只眼中的3次注射发生了视网膜裂孔或孔源性视网膜脱离，每次注射的总体患病率为0.077%，每只眼为0.29%。
结论
视网膜裂孔和孔源性脱离是玻璃体内注射的罕见并发症。对于有高度近视等易感因素或任何其他玻璃体视网膜疾病的患者，应特别注意预防。
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