Granada Institute for Biomedical Research, University Hospital Complex of Granada/University of Granada, Granada, Spain.
Department of Physical Therapy, University of Granada, Granada, Spain.
Cancer. 2016 Oct 15;122(20):3166-3174. doi: 10.1002/cncr.30172. Epub 2016 Jun 22.
The chronicity status of breast cancer survivors suggests a growing need for cancer rehabilitation. Currently, the use of technology is a promising strategy for providing support, as reflected in the emergence of research interest in Web-based interventions in cancer survivorship.
A randomized controlled trial was conducted that included a total of 81 participants who had completed adjuvant therapy (except hormone treatment) for stage I to IIIA breast cancer. Participants were randomly assigned to an 8-week Internet-based, tailored exercise program (n = 40) or to a control group (n = 41).The instruments used at baseline, 8 weeks, and 6-month follow-up were the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire Core 30 and its breast cancer module, the Brief Pain Inventory, the handgrip dynamometer, the isometric abdominal test, the back dynamometer, the multiple sit-to-stand test, and the Piper Fatigue Scale.
After the intervention, the telerehabilitation group had significantly improved scores for global health status, physical, role, cognitive functioning, and arm symptoms (all P < .01) as well as pain severity (P = .001) and pain interference (P = .045) compared with the control group. Significant improvements also were observed favoring the telerehabilitation group for affected and nonaffected side handgrip (both P = .006), abdominal, back and lower body strength (all P < .01), and total fatigue (P < .001). These findings were maintained after 6 months of follow-up, except for role functioning, pain severity, and nonaffected side handgrip. Analysis was based on an intention-to-treat principle.
This program may improve adverse effects and maintain benefits in breast cancer survivors. The results of this study have encouraging implications for cancer care. Cancer 2016;122:3166-74. © 2016 American Cancer Society.
乳腺癌幸存者的慢性状态表明,癌症康复的需求日益增长。目前,技术的应用是提供支持的一种有前途的策略,这反映在癌症生存研究中对基于网络的干预措施的研究兴趣不断增加。
进行了一项随机对照试验,共纳入 81 名已完成 I 期至 IIIA 期乳腺癌辅助治疗(激素治疗除外)的参与者。参与者被随机分配到 8 周的基于互联网的、个性化的锻炼计划(n = 40)或对照组(n = 41)。在基线、8 周和 6 个月随访时使用的工具是欧洲癌症研究与治疗组织生活质量问卷核心 30 及其乳腺癌模块、简明疼痛量表、握力测力计、等长腹部测试、背部测力计、多次坐立测试和派珀疲劳量表。
干预后,远程康复组的全球健康状况、身体、角色、认知功能和手臂症状(均 P <.01)以及疼痛严重程度(P =.001)和疼痛干扰(P =.045)的评分均显著改善,与对照组相比。远程康复组在受影响和未受影响侧握力(均 P =.006)、腹部、背部和下半身力量(均 P <.01)和总疲劳(P <.001)方面也观察到明显的改善。这些发现在 6 个月的随访后仍然存在,除了角色功能、疼痛严重程度和未受影响侧握力。分析基于意向治疗原则。
该方案可能改善乳腺癌幸存者的不良反应并保持获益。本研究结果为癌症护理提供了令人鼓舞的启示。癌症 2016;122:3166-74。© 2016 美国癌症协会。