女性生殖器切割与丙型肝炎在埃及的传播。

Female Genital Cutting and Hepatitis C Spread in Egypt.

作者信息

Kenyon Chris, Buyze Jozefien, Apers Ludwig, Colebunders Robert

机构信息

HIV/STD Unit, Institute of Tropical Medicine, Antwerp, Nationalestraat 155, 2000 Antwerp, Belgium; Division of Infectious Diseases and HIV Medicine, University of Cape Town, Anzio Road, Observatory 7700, South Africa.

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Nationalestraat 155, 2000 Antwerp, Belgium.

出版信息

ISRN Hepatol. 2013 May 7;2013:617480. doi: 10.1155/2013/617480. eCollection 2013.

DOI:10.1155/2013/617480

PMID:27335830

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4890867/

Abstract

A recent analysis of Egypt's first nationally representative survey of hepatitis C virus (HCV) infection found female genital cutting (FGC) to be an independent risk factor for HCV infection for women in urban areas. We use the same dataset to extend this analysis. In an ecological analysis, we find a strong association between FGC and HCV prevalence (Pearson R (2)-74%; P < 0.0001). HCV prevalence is significantly higher if FGC is performed by a non-Doctor (15.4%) than a Doctor (4.2%; P < 0.001), and the calculated population attributable fraction of FGC for prevalent HCV seropositivity is high in women (79.8%).

摘要

最近一项对埃及首次具有全国代表性的丙型肝炎病毒（HCV）感染调查的分析发现，女性生殖器切割（FGC）是城市地区女性感染HCV的一个独立危险因素。我们使用相同的数据集来扩展这一分析。在一项生态分析中，我们发现FGC与HCV流行率之间存在很强的关联（皮尔逊R（2）-74%；P<0.0001）。由非医生进行女性生殖器切割的情况下，HCV流行率（15.4%）显著高于由医生进行切割的情况（4.2%；P<0.001），并且在女性中，针对HCV血清阳性流行情况计算得出的FGC人群归因分数很高（79.8%）。