Kharakter Zh Z, Pavlenko A V
Probl Tuberk. 1989(4):27-30.
The treatment efficacy was studied in 90 patients with destructive tuberculosis of the lungs. 50 of them were subjected to combined chemotherapy with inclusion of sodium nucleinate and 40 were treated with the tuberculostatics alone. It was shown that sodium nucleinate improved the host metabolism and in particular increased nucleonemia. As compared to the controls in the patients treated with sodium nucleinate there was a decrease in the periods of the host disintoxication, discontinuation of tubercle bacilli isolation and closing of destructive cavities. Sodium nucleinate was satisfactorily tolerated by the patients, it induced no adverse reactions and had a favourable effect on the patients immunity.
对90例肺毁损性结核患者的治疗效果进行了研究。其中50例接受了包含核酸钠的联合化疗，40例仅接受抗结核药治疗。结果表明，核酸钠改善了机体代谢，尤其是提高了核子血症。与对照组相比，接受核酸钠治疗的患者机体解毒期缩短、结核杆菌停止排出且毁损空洞闭合。患者对核酸钠耐受性良好，未引起不良反应，且对患者免疫力有积极影响。
