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常见鼠尾草属植物药理学与临床方面的批判性综述

A Critical Overview on the Pharmacological and Clinical Aspects of Popular Satureja Species.

作者信息

Jafari Fereshteh, Ghavidel Fatemeh, Zarshenas Mohammad M

机构信息

Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

J Acupunct Meridian Stud. 2016 Jun;9(3):118-27. doi: 10.1016/j.jams.2016.04.003. Epub 2016 Apr 30.

DOI:10.1016/j.jams.2016.04.003
PMID:27342885
Abstract

Throughout the world, various parts of most Satureja species are traditionally used to treat patients with various diseases and complications. As for the presence of different classes of metabolites in Satureja and their numerous ethnomedical and ethnopharmacological applications, many species have been pharmacologically evaluated. The current work aimed to compile information from pharmacological studies on this savory for further investigations. The keyword Satureja was searched through Scopus and PubMed up to January 1, 2016. We found nearly 55 papers that dealt with the pharmacology of Satureja. We found that 13 species had been evaluated pharmacologically and that Satureja khuzestanica, Satureja bachtiarica, Satureja montana and Satureja hortensis appeared to be the most active, both clinically and phytopharmacologically. Regarding the content of rich essential oil, most evaluations were concerned with the antimicrobial properties. However, the antioxidant, antidiabetic and anticholesterolemic properties of the studied species were found to be good. In addition to the pharmacological activities that have been indentified for some species, opportunities still exist to assess the effectiveness of other well-known species. If different Satureja species are to have extensive ethnopharmacological applications, comprehensive assessments of the acute and chronic toxicities, as well as the teratogenicity, of those plants are needed.

摘要

在世界各地,大多数夏香薄荷属植物的不同部位在传统上被用于治疗患有各种疾病和并发症的患者。至于夏香薄荷属中不同种类代谢物的存在及其众多的民族医学和民族药理学应用,许多物种已经进行了药理学评估。当前的工作旨在汇总关于这种香草的药理学研究信息,以供进一步研究。截至2016年1月1日,通过Scopus和PubMed搜索关键词“夏香薄荷属”。我们发现了近55篇涉及夏香薄荷属药理学的论文。我们发现有13个物种已经进行了药理学评估,并且胡齐斯坦夏香薄荷、巴赫蒂亚里夏香薄荷、山地夏香薄荷和庭园夏香薄荷在临床和植物药理学方面似乎最为活跃。鉴于富含精油的成分,大多数评估都关注抗菌特性。然而,研究发现所研究物种的抗氧化、抗糖尿病和抗胆固醇特性良好。除了已确定的某些物种的药理活性外,评估其他知名物种的有效性的机会仍然存在。如果不同的夏香薄荷属物种要广泛应用于民族药理学,就需要对这些植物的急性和慢性毒性以及致畸性进行全面评估。

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