短柄藤黄茎心材中的新型黄酮类C-O-C二聚体及其他化学成分。

New flavonoid C-O-C dimers and other chemical constituents from Garcinia brevipedicellata stem heartwood.

作者信息

Abderamane Bintou, Tih Anastasie E, Ghogomu Raphael T, Blond Alain, Bodo Bernard

出版信息

Z Naturforsch C J Biosci. 2016;71(7-8):233-41. doi: 10.1515/znc-2015-0125.

DOI:10.1515/znc-2015-0125

Abstract

The methanol extract of the stem heartwood of Garcinia brevipedicellata has furnished three new flavonoid C-O-C dimers, brevipedicilones A (6), B (8) and C (10), along with five previously reported flavonoid dimers, viz. amentoflavone (1), 4″'-O-methylamentoflavone (2), robustaflavone (3), 4'-O-methyl robustaflavone (4) and tetrahinokiflavone (5). The new structures, which are composed of flavanone-flavanonol or flavanonol-flavanonol sub-units, were established based on spectroscopic analysis including 1D and 2D NMR (1H-1H COSY, HSQC, HMBC, and NOESY) spectroscopy, and by comparing their spectral data with those reported for related compounds.

摘要

短柄藤黄茎心材的甲醇提取物得到了三种新的黄酮C-O-C二聚体，短柄藤黄酮A（6）、B（8）和C（10），以及五种先前报道的黄酮二聚体，即穗花杉双黄酮（1）、4″'-O-甲基穗花杉双黄酮（2）、粗壮双黄酮（3）、4'-O-甲基粗壮双黄酮（4）和四氢银杏黄酮（5）。这些由黄烷酮-黄烷醇或黄烷醇-黄烷醇亚基组成的新结构是基于包括一维和二维核磁共振（1H-1H COSY、HSQC、HMBC和NOESY）光谱在内的光谱分析确定的，并通过将它们的光谱数据与相关化合物报道的数据进行比较而确定。