从美国风湿病学家的视角洞察狼疮性肾炎的流行病学及管理
Insights into the epidemiology and management of lupus nephritis from the US rheumatologist's perspective.
作者信息
Hoover Paul J, Costenbader Karen H
机构信息
Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Lupus Center, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
出版信息
Kidney Int. 2016 Sep;90(3):487-92. doi: 10.1016/j.kint.2016.03.042. Epub 2016 Jun 22.
Abstract
Lupus nephritis is a common and severe manifestation of systemic lupus erythematosus that disproportionately affects nonwhites and those in lower socioeconomic groups. This review discusses recent data on the incidence, prevalence, and outcomes of patients with lupus nephritis with a focus on low-income US Medicaid patients. We also review recent guidelines on diagnosis, treatment, and screening for new onset and relapses of lupus nephritis. Finally, we discuss the management of lupus nephritis from a rheumatologist's perspective, including vigilance for the common adverse events related to disease and treatment, and we review prevention and new treatment strategies.
摘要
狼疮性肾炎是系统性红斑狼疮常见且严重的表现形式，对非白种人和社会经济地位较低的人群影响尤为严重。本综述讨论了狼疮性肾炎患者的发病率、患病率及预后的最新数据，重点关注美国低收入医疗补助患者。我们还回顾了狼疮性肾炎新发和复发的诊断、治疗及筛查的最新指南。最后，我们从风湿病学家的角度讨论狼疮性肾炎的管理，包括对与疾病及治疗相关常见不良事件的警惕性，并回顾预防措施和新的治疗策略。
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