Benning Stephen D, Kovac Megan, Campbell Alana, Miller Stephanie, Hanna Eleanor K, Damiano Cara R, Sabatino-DiCriscio Antoinette, Turner-Brown Lauren, Sasson Noah J, Aaron Rachel V, Kinard Jessica, Dichter Gabriel S
Department of Psychology, University of Nevada at Las Vegas, Las Vegas, NV, USA.
New York Presbyterian-Weill Cornell Medical Center, New York, NY, USA.
J Autism Dev Disord. 2016 Sep;46(9):3068-77. doi: 10.1007/s10803-016-2845-y.
We examined the late positive potential (LPP) event related potential in response to social and nonsocial stimuli from youths 9 to 19 years old with (n = 35) and without (n = 34) ASD. Social stimuli were faces with positive expressions and nonsocial stimuli were related to common restricted interests in ASD (e.g., electronics, vehicles, etc.). The ASD group demonstrated relatively smaller LPP amplitude to social stimuli and relatively larger LPP amplitude to nonsocial stimuli. There were no group differences in subjective ratings of images, and there were no significant correlations between LPP amplitude and ASD symptom severity within the ASD group. LPP results suggest blunted motivational responses to social stimuli and heightened motivational responses to nonsocial stimuli in youth with ASD.
我们检测了9至19岁患有（n = 35）和未患有（n = 34）自闭症谱系障碍（ASD）的青少年对社交和非社交刺激的晚期正电位（LPP）事件相关电位。社交刺激是带有积极表情的面孔，非社交刺激与ASD中常见的受限兴趣相关（例如，电子产品、车辆等）。ASD组对社交刺激的LPP波幅相对较小，对非社交刺激的LPP波幅相对较大。两组对图像的主观评分没有差异，ASD组内LPP波幅与ASD症状严重程度之间也没有显著相关性。LPP结果表明，患有ASD的青少年对社交刺激的动机反应减弱，对非社交刺激的动机反应增强。
