Healing of a soft tissue wound of the neck and jaw osteoradionecrosis using platelet gel.

AIM

Bone osteoradionecrosis is a serious complication of radiation treatment. Current treatment approaches are not curative and treatment response is often poor leading to high social and healthcare costs.

CASE REPORT

We report on the first case of osteoradionecrosis with successful restitutio ab integro by repeated administration of platelet gel (PLT-gel) and surgery in a critically ill patient. The administration of PLT-gel during a severe septic episode helped regeneration of bone and soft tissues, shortening the hospital stay of the patient. It was also noted that following applications of PLT-gel, both the use of morphine and the numbers of infective episodes were reduced.

CONCLUSION

Additional studies are needed to confirm the promising effect of PLT-gel for the treatment of osteoradionecrosis.