Nursing Research and EBP Unit - Health Professions Department, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Transfusion Medicine Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Medicine (Baltimore). 2023 Aug 25;102(34):e34779. doi: 10.1097/MD.0000000000034779.
Acute radiodermatitis is a significant complication of cancer radiotherapy, and platelet-based therapies are emerging as potential new treatments.
In this report, we present the case of a patient with head and neck cancer undergoing radiotherapy combined with the monoclonal antibody cetuximab. After 4 weeks of this treatment, the patient developed cutaneous radiation dermatitis. Despite receiving standard treatment with corticosteroids and emollient cream, the lesion did not improve.
cutaneous radiation dermatitis on head and neck cancer patient.
Topical application of platelet gel was initiated on the wound. From the second week of radiotherapy to the 4th week, homologous platelet-rich plasma was applied on the dermatitis using a bandage, 4 times a day.
The topical treatment with homologous platelet gel resulted in complete healing of the radiodermatitis, including restoration of the epidermis, reepithelialization, and reduction in associated pain.
homologous platelet gel might be an alternative to standard treatment of radiation dermatitis.
急性放射性皮炎是癌症放疗的一种严重并发症，基于血小板的治疗方法正作为一种新的潜在治疗方法出现。
在本报告中，我们介绍了一位头颈部癌症患者接受放射治疗联合单克隆抗体西妥昔单抗治疗的情况。在接受这种治疗 4 周后，患者出现皮肤放射性皮炎。尽管接受了皮质类固醇和保湿霜的标准治疗，但病变没有改善。
头颈部癌症患者的皮肤放射性皮炎。
在伤口上开始应用血小板凝胶。从放射治疗的第 2 周到第 4 周，每天 4 次使用绷带在皮炎处应用同源富血小板血浆。
同源血小板凝胶的局部治疗导致放射性皮炎完全愈合，包括表皮恢复、再上皮化和相关疼痛减轻。
同源血小板凝胶可能是放射性皮炎标准治疗的一种替代方法。
